Epstein-Barr Virus (EBV)-associated Haemophagocytic Syndrome

Lorenza Torti, Luigi Maria Larocca, Giuseppina Massini, Luciana Teofili

Abstract


We describe the case of a 17- year old female who developed fatal haemophagocytic syndrome (HPS) one month following acute infection caused by Epstein-Barr virus (EBV). Despite initiation of treatment and reduction of EBV load, laboratory signs of HPS as severe cytopenia, hypofibrinogenemia, hyperferritinemia and hypertriglyceridemia persisted, and the patient died of multiorgan failure. HPS is a rare, but life-threatening complication of EBV infection.


Keywords


EBV, hemophagocytic syndrome

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Mediterr J Hematol Infect Dis ISSN 2035-3006

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