Cauda equina enhancing lesion in a HIV-positive patient. Case report and literature revision.

Pasquale De Bonis, Antonella Cingolani, Angelo Pompucci, Tommaso Tartaglione, Luigi Maria Larocca, Luciana Teofili
  • Pasquale De Bonis
    Affiliation not present
  • Antonella Cingolani
    Affiliation not present
  • Angelo Pompucci
    Affiliation not present
  • Tommaso Tartaglione
    Affiliation not present
  • Luigi Maria Larocca
    Affiliation not present
  • Luciana Teofili
    Pasquale De Bonis1, Antonella Cingolani2, Angelo Pompucci1, Tommaso Tartaglione3, Luigi M. Larocca4 and Luciana Teofili5, Italy |


We describe the case a spinal cord localization of neurological toxoplasmosis in a HIV-positive patient with Burkitt lymphoma, previously treated with chemotherapy and immunotherapy. This complication occurred while patient was in complete remission of lymphoma, with CD4+ T cell count of 270 /ml, undetectable HIV viremia, and despite the trimethoprim/ sulfamethoxazole prophylaxis. Indeed, we hypothesize that in our patient neurologic toxoplasmosis has been fostered more by previous immuno-chemotherapy than by HIV- related immunodeficiency. On the whole, this case suggests that parameters usually employed to predict the risk for opportunistic infections in HIV-positive people might not apply to patients with HIV-related lymphomas.


HIV, Lymphoma, Parassitosis

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Submitted: 2014-06-12 16:05:01
Published: 2011-10-02 00:00:00
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