Epstein-Barr Virus (EBV)-associated Haemophagocytic Syndrome

Lorenza Torti, Luigi Maria Larocca, Giuseppina Massini, Luciana Teofili
  • Lorenza Torti
    Affiliation not present
  • Luigi Maria Larocca
    Affiliation not present
  • Giuseppina Massini
    Affiliation not present


We describe the case of a 17- year old female who developed fatal haemophagocytic syndrome (HPS) one month following acute infection caused by Epstein-Barr virus (EBV). Despite initiation of treatment and reduction of EBV load, laboratory signs of HPS as severe cytopenia, hypofibrinogenemia, hyperferritinemia and hypertriglyceridemia persisted, and the patient died of multiorgan failure. HPS is a rare, but life-threatening complication of EBV infection.


EBV, hemophagocytic syndrome

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Submitted: 2014-06-13 09:32:40
Published: 2012-01-25 00:00:00
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