Bilateral Pleural Effusions due to Pulmonary Amyloidosis as the Presenting Manifestation of Multiple Myeloma

Abhishek Agarwal, Sandeep Singla, Meghana Bansal, Bijay Nair
  • Abhishek Agarwal
    University of Arkansas for Medical Sciences, United States | AAgarwal@uams.edu
  • Sandeep Singla
    Affiliation not present
  • Meghana Bansal
    Affiliation not present
  • Bijay Nair
    Affiliation not present

Abstract

Multiple myeloma is a hematologic malignancy of plasma cell origin. Pleural effusion may develop in the setting of myeloma due to various reasons but is extremely uncommon as a presenting symptom.  A 69-year-old Caucasian man presented with pleural effusions of undetermined etiology after extensive work up, and multiple failed pleurodesis. Lung biopsy revealed pulmonary amyloidosis and led to the diagnosis of multiple myeloma. Patient was started on chemotherapy but died within 6 weeks of his diagnosis due to multiorgan failure. Pulmonary amyloidosis should be suspected as a cause of intractable pleural effusions, even in patient who do not have evidence of lung involvement on imaging studies or typical features of multiple myeloma. Pleural effusions due to amyloidosis are often refractory to treatment, and a high index of suspicion is required for early diagnosis and treatment.

Keywords

pleural effusions, pulmonary amyloidosis, multiple myeloma

Full Text:

PDF
HTML
Submitted: 2014-06-13 09:32:45
Published: 2012-01-25 00:00:00
Search for citations in Google Scholar
Related articles: Google Scholar
Abstract views:
210

Views:
PDF
96
HTML
2919

Article Metrics

Metrics Loading ...

Metrics powered by PLOS ALM


Copyright (c) 2016 Mediterranean Journal of Hematology and Infectious Diseases

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

 

The Mediterranean Journal of Hematology and Infectious Diseases [eISSN 2035-3006] is owned by the U.C.S.C. and it is published by PAGEPress®, Pavia, Italy. All credits and honors to PKP for their OJS.
 
 
© PAGEPress 2008-2017     -     PAGEPress is a registered trademark property of PAGEPress srl, Italy.     -     VAT: IT02125780185