Brain abscesses caused by Nocardia paucivorans in a multiple myeloma patient treated with lenalidomide and dexamethasone: a case report and review of literature.

Jacopo Monticelli, Roberto Luzzati, Cristina Maurel, Chiara Rosin, Romina Valentinotti, Claudio Farina
  • Roberto Luzzati
    Azienda Ospedaliera Universitaria di Trieste, Italy
  • Cristina Maurel
    Azienda Ospedaliera Universitaria di Trieste, Italy
  • Chiara Rosin
    Azienda Ospedaliera Universitaria di Trieste, Italy
  • Romina Valentinotti
    Azienda Ospedaliera Universitaria di Trieste, Italy
  • Claudio Farina
    Microbiology and Virology Institute, AO "Papa Giovanni XXIII", Bergamo, Italy

Abstract

We report the first case of multiple brain abscesses caused by Nocardia paucivorans in a patient suffering from multiple myeloma on treatment with lenalidomide and dexamethasone. Nocardia  paucivorans is a recently described species of the genus Nocardia, which is supposed to have a heightened neurotropism in cases of disseminated infection. Although nocardiosis itself is an uncommon infectious complication in multiple myeloma so far, nocardial brain abscess should be added to the spectrum of adverse effects due to this novel chemotherapy regimen.

Keywords

Nocardia paucivorans, Brain Abscess, Multiple Myeloma, Lenalidomide

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Submitted: 2014-10-16 18:28:09
Published: 2014-12-24 00:00:00
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