High level of HBV DNA virus in the breast milk seems not to contraindicate breastfeeding

Ana Montoya-Ferrer, Astrid Marina Zorrilla, Johannes Viljoen, Jean Pierre Moles, Marie-Louise Newell, Philippe Van de Perre, Edouard Tuaillon
  • Ana Montoya-Ferrer
    Département des Maladies Infectieuses et Tropicales, Centre Hospitalier Régional Universitaire de Montpellier, France, France | a-montoyaferrer@chu-montpellier.fr
  • Astrid Marina Zorrilla
    University of Florida College of Medicine, Gainesville, Florida, United States, United States
  • Johannes Viljoen
    Africa Centre for Health and Population Studies, University of KwaZulu-Natal, Durban, South Africa, South Africa
  • Jean Pierre Moles
    Université Montpellier 1, Inserm U1058, Montpellier, France, France
  • Marie-Louise Newell
    Faculty of Medicine, University of Southampton, Southampton, United Kingdom
  • Philippe Van de Perre
    Département de Bactériologie-Virologie, Centre Hospitalier Universitaire de Montpellier, France, France
  • Edouard Tuaillon
    Département de Bactériologie-Virologie, Centre Hospitalier Universitaire de Montpellier, France, France

Abstract

Concerns of possible risk of mother to child HBV transmission through breastfeeding arouse when mothers present high levels of HBV DNA in breast milk. Here we describe the case of an HIV-HBV coinfected mother who presents a highly replicative HBV infection postdelivery and showed high level of HBV DNA in breast milk. Despite cumulative exposure to HBV infectious particles during breastfeeding, the child, who had been correctly vaccinated, was not infected by HBV.

Keywords

hepatitis B virus, HIV, breastmilk, breastfeeding transmission, cumulative exposure

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Submitted: 2015-04-12 22:39:40
Published: 2015-07-01 00:00:00
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