CHRONIC LYMPHOCYTIC LEUKAEMIA: CENSUS OF PATIENTS TREATED IN ITALIAN HAEMATOLOGY UNITS

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Gianfranco Salvi

Keywords

Chronic Lymphocytic Leukaemia, Epidemiology, Haematology, Census, Survey, Corrections

Abstract

 

 

This study was conducted by contacting the population of the Italian haematology units and collecting from 68% of them data concerning the number of patients with chronic lymphocytic leukaemia visited over the previous 12 months, with the aim of obtaining an overview of the treatment of this disease and comparing the results with the prevalence estimates found in literature.

The projection obtained (about 17,000 patients visited in the previous 12 months) is probably overestimated because of double-counting of patients who may have been treated at two different facilities during the year, although it is also underestimated since the internal medicine units were not involved. The balance of these two opposite factors is not known.

It is important to bear in mind the approximation with which the count was performed in facilities for which no official data were available.

Albeit with these limits, the results obtained are in line with some existing prevalence data and make it possible to determine the portion of patients at different Binet stages and in the various age ranges, identifying the corresponding therapeutic treatments. Use of the CIRS scale to classify patients as FIT and UNFIT was seen to be still somewhat limited.

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References

[1] AIRTUM – Associazione Italiana Registri Tumori, «I tumori in Italia – rapporto AIRTUM 2006», Anno 30, supplemento 2, E&P - Epidemiologia e Prevenzione - Rivista dell’associazione italiana di epidemiologia, http://www.registri-tumori.it/incidenza1998-2002/rapporto/Schede%20specifiche%20per%20tumore/Leucemia%20linfatica%20cronica.pdf, Gennaio - Febbraio 2006.

[2] AIRTUM – Associazione Italiana Registri Tumori, «I tumori in Italia – rapporto AIRTUM 2009», Anno 33 (4-5) supplemento 1, E&P - Epidemiologia e Prevenzione - Rivista dell’associazione italiana di epidemiologia, http://www.registri-tumori.it/PDF/AIRTUM2009Trend/E&P33_4-5S1_94_llc.pdf, Luglio - Ottobre 2009.

[3] AIRTUM – Associazione Italiana Registri Tumori, «I tumori in Italia – rapporto AIRTUM 2010», Anno 34 (5-6) supplemento 2, E&P - Epidemiologia e Prevenzione - Rivista dell’associazione italiana di epidemiologia, http://www.registri-tumori.it/PDF/AIRTUM2010Prevalenza/140_prev_schede.pdf, Settembre - Dicembre 2010.

[4] AIRTUM – Associazione Italiana Registri Tumori, «Banca dati ITACAN», http://itacan.ispo.toscana.it/italian/itacan.htm, Dati raccolti da AIRTUM dal 2006 al 2009.

[5] Brenner H, Gondos A, Pulte D, «Trends in long-term survival of patients with chronic lymphocytic leukemia from the 1980s to the early 21st century», http://www.bloodjournal.org/content/111/10/4916, Blood., 111:4916-214, 2008.

[6] GlobalData, «Chronic lymphocytic leukemia epidemiology forecast to 2023», http://store.globaldata.com/market-reports/pharmaceuticals-and-healthcare/opportuityanalyzer-chronic-lymphocytic-leukemia-opportunity-analysis-and-forecasts-to-2018#.VIsCe7fu3cs, May 2014.

[7] National Cancer Institute, «SEER Cancer Statistics Review 1975-2011», Rapporto annuale del Cancer Institute su tutti i tipi di tumore negli Stati Uniti, http://seer.cancer.gov/csr/1975_2011/browse_csr.php, 2014.

[8] Orphanet, «Prevalenza delle Malattie Rare: Dati bibliografici», I Quaderni di Orphanet N.2, http://www.aslromah.it/operatori/dipartimenti/malattierare/doc/areao/Prevalenza%20delle%20MR%202.pdf, Novembre 2013 .

[9] Redaelli A, Laskin BL, Stephens JM, Botteman MF, Pashos CL, «The clinical and epidemiological burden of Chronic Lymphocytic Leukemia» European Journal of Cancer Care, http://www.ncbi.nlm.nih.gov/pubmed/15196232, July2014.

[10] Rozman C, Montserrat E, «Chronic Lymphocytic Leukemia», New England Journal of Medicine, http://www.ncbi.nlm.nih.gov/pubmed/7675049?dopt=AbstractPlus, http://www.nejm.org/doi/full/10.1056/NEJM199510193331606, November 1995.

[11] Sant M, Allemani C, Tereanu C, De Angelis R, Capocaccia R, Visser O, Marcos-Gragera R, Maynadié M, Simonetti A, Lutz JM, Berrino F, and the HAEMACARE Working Group, «Incidence of hematologic malignancies in Europe by morphologic subtype: results of the HAEMACARE project», Blood, http://www.bloodjournal.org/content/116/19/3724?sso-checked=true, November 2010.