Increased mortality in male recipients of red cells from ever pregnant female donors : mHAGs on red cells to blame ?

Kanjaksha Ghosh

Abstract

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Keywords

mHag, Female to male transfusion , Death

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Submitted: 2017-12-04 11:52:42
Published: 2018-01-01 00:00:00
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References

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Verdijk RM, Kloosterman A, Pool J, et al. Pregnancy induces minor histocompatibility antigen-specific cytotoxic T cells: implications for stem cell transplantation and immunotherapy. Blood.2004; 103: 1961–4. https://doi.org/10.1182/blood-2003-05-1625 PMid:14592836

Desmarets M, Cadwell CM, Peterson KR, Neades R, Zimring JC Minor histocompatibility antigens on transfused leuko reduced units of red blood cells induce bone marrow transplant rejection in a mouse model. Blood. 2009;114: 2315-22. https://doi.org/10.1182/blood-2009-04-214387 PMid:19525479 PMCid:PMC2745850

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