5-Azacytidine in chronic myelomonocytic leukemia: case report and review of literature

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Mariangela Greco
Marianna Criscuolo
Luana Fianchi
Livio Pagano
Maria Teresa Voso


CMML, 5-azacytidine


Hypomethylating drugs are useful in the management of Myelodysplastic syndromes, but  there are only few reports on chronic myelomonocycitic (CMML) leukemia patients. We describe our experience in 3 CMML patients treated with azacitidine. Two patients obtained partial response after 4 treatment cycles with only minor toxicity and are in continuous partial response, with stable peripheral blood counts, at 29 and 30 cycles from treatment start.


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