EPIDEMIOLOGY AND TREATMENT OF ACUTE PROMYELOCYTIC LEUKEMIA IN LATIN AMERICA

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Eduardo Magalhães Rego *
Rafael Henriques Jácomo
(*) Corresponding Author:
Eduardo Magalhães Rego | emrego@hcrp.fmrp.usp.br

Abstract

Distinct epidemiological characteristics have been described in Acute Promielocytic Leukemia (APL). Populations from Latin America have a higher incidence of APL and in some geographic areas a distinct distribution of the PML-RARA isoforms is present. Here, we review the main differences in APL epidemilogy in Latin America as well as treatment outcomes.


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Author Biography

Eduardo Magalhães Rego, National Institute of Science and Technology in Stem Cell and Cell Therapy, Division of Oncology/Hematology, Department of Internal Medicine, Medical School of Ribeirão Preto, University of São Paulo,

    1   Corresponding author: Eduardo Magalhães Rego, Division of Oncology/Hematology, Department of Internal Medicine; Medical School of Ribeirão Preto, University of São Paulo, Av. Bandeirantes 3900, CEP 14049-900, Ribeirão Preto, SP, Brazil. Phone: (55)(16) 36022888, Fax: (55)(16) 36336695. Email: emrego@hcrp.fmrp.usp.br