Michele Malagola1, Benedetta Rambaldi1, Giuseppe Ravizzola2, Chiara Cattaneo3, Erika Borlenghi3, Nicola Polverelli1, Alessandro Turra1, Enrico Morello1, Cristina Skert1, Valeria Cancelli1, Federica Cattina1, Giorgio Giannetta1, Simona Bernardi, Simone Perucca, Camillo Almici4, Aldo Roccaro5, Liana Signorini6, Roberto Stellini6, Francesco Castelli6, Arnaldo Caruso2 and Domenico Russo1.
of Hematology, Clinical and Experimental Sciences Department,
University of Brescia, Bone Marrow Transplant Unit,ASST-Spedali Civili,
Brescia, Italy, Italy
2 Institute of Microbiology, Department of Molecular and Transplational Medicine, University of Brescia, Italy
3 Division of Hematology, ASST-Spedali Civili, Brescia, Italy
4 Laboratory for Stem Cells Manipulation and Cryopreservation, ASST-Spedali Civili, Brescia, Italy
5 ASST-Spedali Civili, Coordinamento e Progettazione Ricerca Clinica, CREA Laboratory, Brescia, Italy
6 Chair of Infectious Diseases, Division of Infectious and Tropical Diseases, University of Brescia, Italy
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stream infections (BSIs) represent a major complication of allo-SCT and
are a major cause of morbidity and mortality during and after bone
Patients and Methods
|Table 1. Clinical and biological characteristics of the 80 allotransplanted patients with BSI vs the 82 allotransplanted patients without BSI.|
|Table 2. Antibiotic resistance of the 119 species isolated from 80 allotransplanted patients.|
|Figure 1A. Overall survival of the 162 allotransplanted patients according to presence or not of a BSI.
Figure 1B. Transplant related mortality of the 162 allotransplanted patients according to presence or not of a BSI. CI= Cumulative Incidence; TRM = Transplant Related Mortality