1 Department of Paediatrics and Child Health, Obafemi Awolowo University, Ile Ife, Osun State, Nigeria.
2 Department of Paediatrics, Obafemi Awolowo University Teaching Hospitals Complex, Ile Ife, Osun State, Nigeria.
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haemoglobin (HbF) is a major modifying factor influencing sickle cell
disease (SCD) severity. Despite this, HbF estimation is not routinely
done in Nigeria. The relationship between HbF and SCD severity among
affected children is also poorly studied.
|Table 1. Socio-demographic characteristics of the 105 subjects.|
|Table 2. Frequency of pain episodes, SCD-related hospitalisation and transfusion among the subjects in the 12 months preceding the study.|
|Table 3. Relationship between foetal haemoglobin levels, socio-demographic and clinical burden of children with sickle cell anaemia.|
|Figure 1. Scatter plots showing the correlation between foetal haemoglobin levels and age of the patients in both sexes.|
|Table 4. Relationship between the mean foetal haemoglobin level and complications of sickle cell anaemia in the subjects.|
|Table 5. Distribution of complications of sickle cell anaemia by the level of foetal haemoglobin.|
AcknowledgementWe appreciate the cooperation of the parents and children who participated in this study.