1 Department of Haematology, Antwerp University Hospital, Edegem, Belgium.
2 Department of Clinical Biology, Antwerp University Hospital, Edegem, Belgium.
3 Clinical Trial Center (CTC), Clinical Research Center (CRC) Antwerp, Antwerp University Hospital, University of Antwerp, Edegem, Belgium.
4 Vaccine & Infectious Disease Institute, Faculty of Medicine & Health Sciences, University of Antwerp, Antwerp, Belgium.
5 StatUa, Center for Statistics, University of Antwerp, Edegem, Belgium.
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of fever in prolonged, profound neutropenia remains challenging with
many possible infectious and non-infectious causes. We investigated
whether procalcitonin (PCT) is superior to C-reactive protein (CRP) in
discriminating between different aetiologies of fever in this setting.
Material and Methods
|Table 1. Characteristics of patients, neutropenic and febrile episodes.|
|Figure 1. Kinetics of CRP and PCT for different aetiologies of febrile neutropenia.|
|Table 2. Kinetics of PCT and CRP for different etiologies of neutropenic fever (median/range).|
|Figure 2. ROC curves.|
|Table 3. Predictive value of CRP on day 2 after onset of fever for IFD.|