of Pharmacy, China National Nuclear Corporation 416 Hospital/ The
Second Affiliated Hospital of Chengdu Medical College. China.
2 Hematology Department, China National Nuclear Corporation 416 Hospital/ The Second Affiliated Hospital of Chengdu Medical College. China.
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Deferoxamine (DFO) or Deferiprone (DFP) or Deferasirox (DFX)
monotherapy and DFO and DFP combination therapy (DFO+DFP) were four
commonly implemented now chelation regimens for the iron overloaded of
β-thalassemia major. This systematic review aims to determine the
cost-effectiveness of four chelation regimens and provide evidence for
the rational use of chelation regimens for β-thalassemia major therapy
in the clinic.
|Figure 1. Flow diagram of articles identified and evaluated.|
|Table 1. The characters of included papers.|
|Table 2. The results of included studies.|
|Table 3. Results of the methodological quality assessment*|
|Table 4. The price of the three iron chelators in the considered countries.|