1 Hematology, Polo Universitario Pontino, S.M. Goretti Hospital, Latina, Italy.
2 Department of Public Health and Infectious Diseases, Sapienza University, S.M. Goretti Hospital, Latina, Italy.
3 Hematology, Dipartimento Medicina Traslazionale e di Precisione, AOU Policlinico Umberto I, Sapienza University of Rome, Italy.
4 Department of Medical Oncology, Sapienza University of Rome, Medical and Surgical Sciences and Biotechnology, Rome, Italy.
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Background: Saprochaete capitata is a rare and emerging opportunistic fungus, involving immunocompromised hosts, in particular, neutropenic patients after chemotherapy.
Case Report: We report a case of disseminated and cerebral infection by Saprochaete capitata,
in a 68-year-old woman affected by acute myeloid leukemia that was
successfully managed with liposomal amphotericin B and isavuconazole.
|Figure 1. A) CT scan. In the left lung is present a 20 mm excavation filled with fluid: air-crescent sign. B) CT scan of the abdomen. Two hypodensae cystic hepatic lesions of 2 and 1.5 cm; other millimetric lesions can be seen (white arrows). C) Brain MRI: T2 weighted sequence. An 11 mm cystic lesion is present in the left head of the caudate nucleus, with compression of the left lateral ventricle. Mild peri-lesional edema is present. D) Brain MRI: T1 weighted gadolinium contrast-enhanced sequences. The same cystic lesion showing a concentric rim of contrast.|
|Figure 2. CT scan after 8 months from S. capitata infection. A) In the left lung is present a 7 mm excavation scar (white arrow). B) CT scan of the abdomen. Shrunken hypodensae cystic hepatic lesion of 11 mm. C) Brain CT: A 9 mm cystic lesion surrounded by concentric rim is present in the left head of the caudate nucleus.|