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Although the etiology of Kawasaki disease (KD) remains elusive, the available evidence indicates that the primum movens may be a dysregulated immune response to various microbial agents, leading to cytokine cascade and endothelial cell activation in patients with KD. Documented infections by different viruses in many individual cases have been largely reported and are discussed herein, but attempts to demonstrate their causative role in the distinctive KD scenario and KD epidemiological features have been disappointing. To date, no definite link has been irrefutably found between a single infection and KD.
The History of Kawasaki Disease
A Systemic Vasculitis is the Key to Explain Kawasaki Disease
The Clinical Chameleon of Kawasaki Disease
Different Potential Causes, One Resulting Disease
A Viral Infection to Switch on Kawasaki Disease
|Table 1. Viral agents associated with Kawasaki disease.|
The Outbreak of the New Coronavirus and Kawasaki Disease
The Evidence about Viral Contributors to Kawasaki Disease