@article{Bayram_Devrim_Apa_Gülfidan_Türkyılmaz_Günay_2013, title={SPHINGOMONAS PAUCIMOBILIS INFECTIONS IN CHILDREN: NOSOCOMIAL VERSUS COMMUNITY ACQUIRED INFECTIONS}, volume={5}, url={https://www.mjhid.org/mjhid/article/view/2013.040}, DOI={10.4084/mjhid.2013.040}, abstractNote={<span style="font-family: Times New Roman; font-size: small;"> </span><p class="MsoNormal" style="margin: 0cm 0cm 0pt; text-align: justify; line-height: 200%; mso-layout-grid-align: none;"><em><span style="line-height: 200%; font-family: "Arial","sans-serif"; font-size: 12pt; mso-ansi-language: EN-GB;" lang="EN-GB">Sphingomonas paucimobilis</span></em><span style="line-height: 200%; font-family: "Arial","sans-serif"; font-size: 12pt; mso-ansi-language: EN-GB;" lang="EN-GB"> is a <span style="mso-bidi-font-style: italic;">causative agent of infection in immunocompromised </span></span><span style="line-height: 200%; font-family: "Arial","sans-serif"; font-size: 12pt; mso-ansi-language: EN-GB; mso-bidi-font-style: italic;" lang="EN-GB">patients, and h</span><span class="st1"><span style="line-height: 200%; font-family: "Arial","sans-serif"; font-size: 12pt; mso-ansi-language: EN-GB;" lang="EN-GB">ealthcare-associated infections. </span></span><span style="line-height: 200%; font-family: "Arial","sans-serif"; font-size: 12pt; mso-ansi-language: EN-GB;" lang="EN-GB">Although the infections associated with <em>S.paucimobilis</em><span style="mso-bidi-font-style: italic;"> occurs rarely, </span>it has been encountered with increasing frequency in clinical settings. In the current study we noted the risk factors and clinical features of the children with <em>S.paucimobilis </em><span style="mso-bidi-font-style: italic;">infections, and </span>the antimicrobial susceptibilities of the isolated strains among the patients. </span></p><span style="font-family: Times New Roman; font-size: small;"> </span><p class="MsoNormal" style="margin: 0cm 0cm 0pt; text-align: justify; line-height: 200%; mso-layout-grid-align: none;"><span style="line-height: 200%; font-family: "Arial","sans-serif"; font-size: 12pt; mso-ansi-language: EN-GB;" lang="EN-GB">This study was conducted in Dr. Behçet Uz Children’s Hospital, Turkey, during the period of January 2005 and December 2012. The medical records of pediatric patients with positive cultures for <em>S.paucimobilis </em>were reviewed.</span></p><span style="font-family: Times New Roman; font-size: small;"> </span><p class="MsoNormal" style="margin: 0cm 0cm 0pt; text-align: justify; line-height: 200%; mso-layout-grid-align: none;"><em><span style="line-height: 200%; font-family: "Arial","sans-serif"; font-size: 12pt; mso-ansi-language: EN-GB;" lang="EN-GB">Sphingomonas paucimobilis</span></em><span style="line-height: 200%; font-family: "Arial","sans-serif"; font-size: 12pt; mso-ansi-language: EN-GB;" lang="EN-GB"> isolates were recovered from 24 pediatric patients. The median age was 4 years (ranging from 3 days infant to 15 years) and 58,3% were male.<span style="mso-spacerun: yes;"> </span>Eight (33,3%) of the patients were under 1 months of age. Among the patients; 13 (54,2%) infections were community related however 11(45.8%) infections were nosocomial infection. The median duration of hospital stay was 7 days (ranging from 4 to 22 days). The most effective antibiotics were fluoroquinolones, carbapenems, and trimethoprim/sulfamethoxazole. </span></p><span style="font-family: Times New Roman; font-size: small;"> </span><p class="MsoNormal" style="margin: 0cm 0cm 0pt; text-align: justify; line-height: 200%; mso-layout-grid-align: none; mso-pagination: none;"><span style="line-height: 200%; font-family: "Arial","sans-serif"; font-size: 12pt; mso-ansi-language: EN-GB;" lang="EN-GB">T</span><span style="line-height: 200%; font-family: "Arial","sans-serif"; font-size: 12pt; mso-ansi-language: EN-US; mso-bidi-font-style: italic;" lang="EN-US">his is the first largest study in children </span><span style="line-height: 200%; font-family: "Arial","sans-serif"; font-size: 12pt; mso-ansi-language: EN-US;" lang="EN-US">to evaluate the clinical features of <em>S. paucimobilis</em> infections. </span><em><span style="line-height: 200%; font-family: "Arial","sans-serif"; font-size: 12pt; mso-ansi-language: EN-GB;" lang="EN-GB">Sphingomonas paucimobilis</span></em><span style="line-height: 200%; font-family: "Arial","sans-serif"; font-size: 12pt; mso-ansi-language: EN-GB;" lang="EN-GB"> </span><span style="line-height: 200%; font-family: "Arial","sans-serif"; font-size: 12pt; mso-ansi-language: EN-US;" lang="EN-US">may cause infections in both previously healthy and immunocompromised children. </span><span style="line-height: 200%; font-family: "Arial","sans-serif"; font-size: 12pt; mso-ansi-language: EN-GB;" lang="EN-GB">Although variable antimicrobial regimens were achieved to the patients, <span class="hps">t</span>here was no attributable fatality due to <em style="mso-bidi-font-style: normal;">S.paucimobilis</em> infections due to the <span class="hps">low</span><span class="shorttext"> </span><span class="hps">virulence of the bacteria.</span> </span></p><span style="font-family: Times New Roman; font-size: small;"> </span>}, number={1}, journal={Mediterranean Journal of Hematology and Infectious Diseases}, author={Bayram, Nuri and Devrim, İlker and Apa, Hurşit and Gülfidan, Gamze and Türkyılmaz, Hande Namal and Günay, İlker}, year={2013}, month={Jun.}, pages={e2013040} }