@article{Galli_Bellesi_Viscovo_Sorà_Hohaus_Piccirillo_Laurenti_Chiusolo_De Stefano_Sica_et al._2021, title={Cytomorphology of Chimeric Antigen Receptor T-Cells (CAR-T)}, volume={13}, url={https://www.mjhid.org/mjhid/article/view/4745}, DOI={10.4084/MJHID.2021.066}, abstractNote={<p style="margin: 0cm; text-align: justify; text-justify: inter-ideograph; line-height: 150%;"><span lang="EN-US" style="font-family: ’Arial’,sans-serif;">Chimeric antigen receptor (CAR) T cells represent one of the newest frontiers of cell therapy. Their application currently involves relapsed/refractory aggressive B cell lymphoma and leukemia as a standard of care, while several studies are exploring CAR-T to treat multiple myeloma and other hematological malignancies. Here we describe the cytomorphology of CAR-T collected from the leftovers of infusion bags, and therefore before the encounter with the antigen, with, among others, a peculiar population of giant lymphoid cells with blastoid features and hypertrophic centrosome. </span></p>}, number={1}, journal={Mediterranean Journal of Hematology and Infectious Diseases}, author={Galli, Eugenio and Bellesi, Silvia and Viscovo, Marcello and Sorà, Federica and Hohaus, Stefan and Piccirillo, Nicola and Laurenti, Luca and Chiusolo, Patrizia and De Stefano, Valerio and Sica, Simona and et al.}, year={2021}, month={Oct.}, pages={e2021066} }