TY - JOUR AU - Perrone, Salvatore AU - Lisi, Chiara AU - Ortu La Barbera, Elettra AU - Luise, Cristina AU - Lichtner, Miriam AU - Girmenia, Corrado AU - Cimino, Giuseppe PY - 2020/04/27 Y2 - 2024/03/28 TI - Isavuconazole therapy of disseminated and encephalic Saprochaete capitata infection in an acute myeloid leukemia patient treated with midostaurin. JF - Mediterranean Journal of Hematology and Infectious Diseases JA - Mediterr J Hematol Infect Dis VL - 12 IS - 1 SE - Case Reports DO - 10.4084/mjhid.2020.026 UR - https://www.mjhid.org/mjhid/article/view/2020.026 SP - e2020026 AB - <p>BACKGROUND<em> Saprochaete capitata</em> is a rare and emerging opportunistic fungus, involving immunocompromised hosts, in particular neutropenic patients after chemotherapy. CASE REPORT We report a case of disseminated and cerebral infection by <em>Saprochaete capitata, </em>in a 68-year-old woman affected by acute myeloid leukemia that was successfully managed with liposomal amphotericin B and isavuconazole. CONCLUSION this case illustrates the feasibility of isavuconazole therapy in the treatment of a <em>S.capitata</em> infection when co-administered with midostaurin.</p> ER -