TY - JOUR AU - Sayed, Madeha Abdalla AU - Abdelhakeem, Mohamed PY - 2022/01/01 Y2 - 2024/03/29 TI - TYPICAL AND ATYPICAL PRESENTATION OF COVID-19 INFECTION IN CHILDREN IN THE TOP OF PANDEMIC IN MINIA GOVERNORATE (TWO CENTER EXPERIENCE) JF - Mediterranean Journal of Hematology and Infectious Diseases JA - Mediterr J Hematol Infect Dis VL - 14 IS - 1 SE - Original Articles DO - 10.4084/MJHID.2022.002 UR - https://www.mjhid.org/mjhid/article/view/4700 SP - e2022002 AB - <p><strong>Back&nbsp;ground: </strong>A novel coronavirus which is identified as cause of pandemic situation&nbsp;inFebruary2020 and affecting adult and children with variable&nbsp;presentation and outcome.</p><p><strong>Objective:&nbsp;</strong>We studied the typical and atypical clinical and&nbsp;laboratory presentation of&nbsp;COVID-19 during the peak of the first wave&nbsp;&nbsp;&nbsp;in two main&nbsp;&nbsp;referral&nbsp;hospitals, upper Egypt&nbsp;El&nbsp;Minya governorate.</p><p><strong>Methods:&nbsp;&nbsp;</strong>Among 88&nbsp;children with&nbsp;suspected cases&nbsp;&nbsp;tested for&nbsp;COVID-19,&nbsp;only 22 who proved to be &nbsp;positive. Studied patients were classified into 3 groups based on age. The first group&nbsp;2–5years,the&nbsp;second&nbsp;for 5–10years and the third one included those aged more than 10 years. All patients met diagnostic guidelines established by Egyptian Ministry of health.</p><p><strong>Results</strong>: out of the positive 22 (25%) patients, 13(59.1%) of them were male, while 9 (40.9%) were females. All enrolled patients have a history of near contact exposure (100%). Thrombocytopenia was the highest presenting symptom in all enrolled patients18(81.8%), while other hematological findings were anemia in 11 (50%), thrombotic symptoms in 2(9.1%), pancytopenia in 2(9.1%) while bleeding was found in 1 patient (4.5%) .Fever 16 (72.7%) the common constitutional symptoms in COVID-19 were not reported in all enrolled patients (0%) while sore throat was reported in only 2 patients (9.1%).Respiratory presentation was only dominant in positive chest CT finding rather than clinical symptoms 17(72.3%) GIT symptom were the dominant presenting feature as vomiting was found in 15 (68.2%), diarrhea in 10 (45.5%), abdominal pain in 11 (50%), jaundice in 9 (40.9%) and dehydration in 6 (27.3%).Neurological symptoms were convulsions in 4(18.2%) while encephalopathy was 2(9.1%).Nephritis was the only renal presentation in the enrolled patients3 (13.6%).Cardiac presentations were only cyanosis 8 (36.4%) and arrhythmias 6 (27.3%)</p><p><strong>Conclusion:&nbsp;</strong>COVID-19 has many clinical&nbsp; classic presentation in children&nbsp; however&nbsp;&nbsp;other&nbsp;non-typical presentation like&nbsp;hematological. CNS and renal presentation has been&nbsp;reported.&nbsp;</p><p>&nbsp;</p> ER -