TY - JOUR AU - Peng, Peng AU - XU, Fengming AU - YI, Jixing AU - LIANG, Bumin AU - TANG, Cheng AU - FENG, Qing PY - 2022/10/29 Y2 - 2024/03/19 TI - COMPARATIVE STUDY ON THE MEASUREMENT OF LIVER T2* VALUES OF THALASSEMIA PATIENTS AND THE CLINICAL GRADING OF LIVER IRON CONCENTRATION BY DIFFERENT POST-PROCESSING SOFTWARE: MEASUREMENT OF LIVER T2* VALUES OF THALASSEMIA JF - Mediterranean Journal of Hematology and Infectious Diseases JA - Mediterr J Hematol Infect Dis VL - 14 IS - 1 SE - Original Articles DO - 10.4084/MJHID.2022.072 UR - https://www.mjhid.org/mjhid/article/view/5033 SP - e2022072 AB - <p><strong>Objective:</strong> To explore the relationship between the liver T2* values of thalassemia patients measured by Circle Cardiovascular Imaging CVI42 (CVI42), CMRtools / Thalassemia Tools (CMRtools) and Excel spreadsheet (Excel), and the three software's accuracy in clinical grading of liver iron concentration (LIC). <strong>Methods: </strong>The liver T2* images thalassemia patients were imported into CVI42 and CMRtools to measure the T2* value. And the signal intensity (SI) of the T2* image, measured in the MR scanning equipment, was input into Excel to calculate T2* value. The relationship of the T2* values measured by the above three software were compared. And LIC clinical grading was performed on the three measured T2* value results, and the LIC (LIC<sub>F</sub>) provided by FerriScan was used as the reference standard to compare the accuracy of the three grading results. <strong>Results: </strong>There was no statistical difference between the T2* values measured by CVI42, CMRtools and Excel (<em>P</em>&gt;0.05), but there was a high degree of consistency between them (<em>P</em>&lt;0.05), and there was a high linear positive correlation between the them (<em>P</em>&lt;0.05). There was no statistical difference between the LIC grading results of CVI42 and CMRtools and the LIC<sub>F</sub> grading results (<em>P</em>&gt;0.05). There is a significant difference between the LIC grading results of Excel and the LIC<sub>F</sub> grading results (<em>P</em>&lt;0.05). <strong>Conclusion</strong>: The liver T2* values measured by CVI42, CMRtools and Excel are equivalent. However, CVI42 and CMRtools have better diagnostic accuracy for LIC clinical grade, while Excel has worse diagnostic accuracy.</p><p>Keywords: THALASSEMIA; lIVER T2 VALUE; </p> ER -