Mediterranean Journal of Hematology and Infectious Diseases

MJHID Educational Clinical Case

Persistent Fever and Splenic Abscess-like Lesions: A Diagnostic Trap in a Young Adult

Supplementary Files

Supplementary table S1. Other published cases of lymphoma presenting as splenic abscess.

CaseAge/SexPathology subtypeImaging findingOutcome

1.1

29/FDLBCLCT: hypodense splenic lesion with central necrosis; no lymphadenopathyResponded to R-CHOP

2.2

47/MDLBCL (extranodal)CT: splenic lesion; subsequent hepatic lesionsDeceased

3.3

63/FDLBCL
(non-germinal center type)		CECT: mild splenomegaly, multiple patchily enhancing SOLs; hilar lymphadenopathy with necrosisReceived CHOP; uneventful 1-year follow-up

4.4

43/MDLBCLCT: enlarged spleen (168 mm), multiple hypodense areas with fluid component, largest 65×57 mmNot reported

5.5

75/FDLBCLCT: well-circumscribed, rounded, low-attenuation lesions; retroperitoneal lymphadenopathyDeceased

6.6

68/MDLBCL
(germinal center type)		US: three well-circumscribed hypoechoic masses; PET-CT: two hypermetabolic lesions

4 cycles R-CHOP; disease-free at 6 months

7.7

55/MDLBCLUS: multiple well-circumscribed hypoechoic lesions; CT: low-attenuation lesions

6 cycles CHOP; disease-free at 6 months

8.8

62/FDLBCL with CD30 expressionCT: 8-cm splenic mass with central necrosis; drain placed for 28 daysNot reported

9.9

74/MMarginal zone lymphomaCT: 8.4×6.2 cm hypodense non-enhancing lesionNot reported

10.10

63/MDLBCL (germinal center type)CT: 5 cm mass with indistinct margins in mid-spleen; PET-CT: FDG-avid (SUVmax 28.3)

3 cycles PvRCHP; disease-free at 5 months

References

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