Letters to the Editor
Vol. 12 No. 1 (2020): Mediterranean Journal of Hematology and Infectious Diseases, Volume 12, 2020

“Hemolysis, or not Hemolysis, that is the question”. Use of hydroxychloroquine in a patient with COVID-19 infection and G6PD deficiency.

Hemolysis by Hemolysis and G6PD deficiency.

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Received: August 18, 2020
Accepted: September 14, 2020
Published: October 27, 2020
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Citations

Costanzo M, De Giglio MAR, Roviello GN. SARS-CoV-2: Recent Reports on Antiviral Therapies Based on Lopinavir/Ritonavir, Darunavir/Umifenovir, Hydroxychloroquine, Remdesivir, Favipiravir and other Drugs for the Treatment of the New Coronavirus. Curr Med Chem. 2020;27(27):4536-4541. https://doi.org/10.2174/0929867327666200416131117 PMid:32297571
ISS COVID-19 Rare Diseases Working Group. Interim guidance for the appropriate support of people with enzymopenia G6PD (favism) in the current SARS-CoV-2 emergency scenario. Version April 14, 2020. Roma: Istituto Superiore di Sanità; 2020. (Rapporto ISS COVID-19, n. 14/2020 - English version).
Beauverd Y, Adam Y, Assouline B, Samii K. COVID-19 infection and treatment with hydroxychloroquine cause severe haemolysis crisis in a patient with glucose-6-phosphate dehydrogenase deficiency [published online ahead of print, 2020 Apr 23]. Eur J Haematol. 2020;10.1111/ejh.13432. https://doi.org/10.1111/ejh.13432 PMid:32324284 PMCid:PMC7264743
Maillart E, Leemans S, Van Noten H, et al. A case report of serious haemolysis in a glucose-6-phosphate dehydrogenase-deficient COVID-19 patient receiving hydroxychloroquine. Infect Dis (Lond). 2020;52(9):659-661.
https://doi.org/10.1080/23744235.2020.1774644 PMid:32496938 PMCid:PMC7284136
Sasi S, Yassin MA, Nair AP, Al Maslamani MS. A Case of COVID-19 in a Patient with Asymptomatic Hemoglobin D Thalassemia and Glucose-6-Phosphate Dehydrogenase Deficiency. Am J Case Rep. 2020;21:e925788. Published 2020 Jul 22.
https://doi.org/10.12659/AJCR.925788 PMid:32697769 PMCid:PMC7394553
De Franceschi L, Costa E, Dima F, Morandi M, Olivieri O. Acute hemolysis by hydroxycloroquine was observed in G6PD-deficient patient with severe COVD-19 related lung injury. Eur J Intern Med. 2020;77:136-137. https://doi.org/10.1016/j.ejim.2020.04.020 PMid:32381323 PMCid:PMC7167571
Roper D, Layton M, Rees D, et al. Laboratory diagnosis of G6PD deficiency. A British Society for Haematology Guideline. Br J Haematol. 2020;189(1):24-38.https://doi.org/10.1111/bjh.16366; PMid:31991476
Pietrapertosa A, Palma A, Campanale D, Delios G, Vitucci A, Tannoia N. Genotype and phenotype correlation in glucose-6-phosphate dehydrogenase deficiency. Haematologica. 2001;86(1):30-35.
Cappellini MD, Fiorelli G. Glucose-6-phosphate dehydrogenase deficiency. Lancet. 2008;371(9606):64-74.
Kassi EN, Papavassiliou KA, Papavassiliou AG. G6PD and chloroquine: Selecting the treatment against SARS-CoV-2?. J Cell Mol Med. 2020;24(9):4913-4914. https://doi.org/10.1111/jcmm.15312 PMid:32281268 PMCid:PMC7205832

How to Cite



“‘Hemolysis, or not Hemolysis, that is the question’. Use of hydroxychloroquine in a patient with COVID-19 infection and G6PD deficiency.: Hemolysis by Hemolysis and G6PD deficiency”. (2020) Mediterranean Journal of Hematology and Infectious Diseases, 12(1), p. e2020076. doi:10.4084/mjhid.2020.076.