MJHID Educational Clinical Cases
Vol. 15 No. 1 (2023): Review Articles, Original Article, Scientific Letter, Case Reports Letter to the Editor
https://doi.org/10.4084/MJHID.2023.028

Orbital Infiltration in a Patient with Waldenström Macroglobulinemia: Need for Multidisciplinary Approach and Comparison with the Literature

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Received: January 31, 2023
Accepted: March 7, 2023
Published: April 28, 2023
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Waldenström’s Macroglobulinemia, Invasive Aspergillosis, Orbital Lymphoma, Bruton Kinase Inhibitors, Lacrimal Glands Lymphoma×

Authors

Riccardo Paggi
paggi.riccardo@gmail.com
1 Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy. , Italy.
Francesca Mariotti
1 Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Italy.
Jessica Mencarini
1 Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; 2 Infectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy., Italy.
Silvia Bresci
2 Infectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy., Italy.
Irene Capolmi
2 Infectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy., Italy.
Filippo Bartalesi
1 Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; 2 Infectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy., Italy.
Beatrice Borchi
2 Infectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy., Italy.
Luca Nassi
3 Hematology Unit, Azienda Ospedaliera Universitaria Careggi, University of Florence, Florence, Italy., Italy.
Alessandro Maria Vannucchi
4 Center for Innovation and Research in Myeloproliferative Neoplasms, Hematology Unit, Azienda Ospedaliera Universitaria Careggi, University of Florence, Florence, Italy., Italy.
Alessandro Bartoloni
1 Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; 2 Infectious and Tropical Diseases Unit, Careggi University Hospital, Florence, Italy., Italy.

The use of specific inhibitory drugs of intracellular signaling pathways (such as Bruton-Kinase inhibitors) for the treatment of Waldenström's macroglobulinemia (WM) is a recognized risk factor for Aspergillus spp. infections. The overlapping clinical manifestations of the two diseases may require the involvement of different medical specialties. 

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“Orbital Infiltration in a Patient with Waldenström Macroglobulinemia: Need for Multidisciplinary Approach and Comparison with the Literature” (2023) Mediterranean Journal of Hematology and Infectious Diseases, 15(1), p. e2023028. doi:10.4084/MJHID.2023.028.
Copyright (c) 2023 Riccardo Paggi, Francesca Mariotti, Jessica Mencarini, Silvia Bresci, Irene Capolmi, Filippo Bartalesi, Beatrice Borchi, Luca Nassi, Alessandro Maria Vannucchi, Alessandro Bartoloni Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.