Bladder microbiota snapshots help to monitor urinary tract infections in vulnerable patients

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Giulia Santarelli
Delia Mercedes Bianco
Margherita Capriati
Maurizio Sanguinetti
Claudia Rendeli
Flavio De Maio

Keywords

Bladder microbiota, urinary tract infections, metagenomics

Abstract

The development of next generation sequencing technology has undoubtedly impairs the classic microbiological approach even though main questions remain still elusive. To date, nobody can define the existence of a unique healthy microbial community, nor a diagnostic application can be definitely assessed. In this context, “snapshots” of the microbiota contribute to reveal factors associated with a disease, even though lacking longitudinal data and the association with results obtained from gold standard microbiological tests. Here we show how the information obtained by microbiota can be a promising additional tool to monitor urinary tract infections revaluating beneficial communities or attention to particularly microbial patterns.

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