Scientific Letters
Vol. 18 No. 1 (2026): Mediterranean Journal of Hematology and Infectious Diseases

Late-onset anicteric veno-occlusive disease after haploidentical HSCT: diagnostic challenges in the setting of CMV reactivation

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Published: June 30, 2026
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References
1. Song Z, Han X, Zhou Z, et al. Comprehensive management of hematopoietic stem cell transplantation complications: from infection prevention to immune microenvironment reconstruction. Front Immunol. 2026;17:1740067.
2. Bonifazi F, Barbato F, Ravaioli F, Sessa M, Defrancesco I, Arpinati M, et al. Diagnosis and treatment of veno-occlusive disease/sinusoidal obstruction syndrome after allogeneic hematopoietic stem cell transplantation. Front Immunol. 2020;11:489.
3. Mohty M, Malard F, Abecassis M, Aerts E, Alaskar AS, Aljurf M, et al. Revised diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a new classification from the European Society for Blood and Marrow Transplantation. Bone Marrow Transplant. 2016;51:906–912.
4. Corbacioglu S, Kernan NA, Pagliuca A, Ryan RJ, Tappe W, Richardson PG. Incidence of anicteric veno-occlusive disease/sinusoidal obstruction syndrome and outcomes with defibrotide following hematopoietic cell transplantation in adult and pediatric patients. Biol Blood Marrow Transplant. 2020;26:1342–1349.
5. Limaye AP, Babu TM, Boeckh M. Progress and challenges in the prevention, diagnosis, and management of cytomegalovirus infection in transplantation. Clin Microbiol Rev. 2020;34:e00043-19.
6. Lee SB, Lee S, Cho YJ, Choi YH, Cheon JE, Hong KT, et al. Shear wave elastography and dispersion imaging for hepatic veno-occlusive disease prediction after pediatric hematopoietic stem cell transplantation: a feasibility study. Pediatr Radiol. 2024;54:1144–1155.
7. Cairo MS, Cooke KR, Lazarus HM, Chao N. Modified diagnostic criteria, grading classification and newly elucidated pathophysiology of hepatic sinusoidal obstruction syndrome/veno-occlusive disease after hematopoietic cell transplantation. Br J Haematol. 2020;190:822–836.
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How to Cite



“Late-onset anicteric veno-occlusive disease after haploidentical HSCT: diagnostic challenges in the setting of CMV reactivation” (2026) Mediterranean Journal of Hematology and Infectious Diseases, 18(1), p. e2026057. doi:10.4084/MJHID.2026.057.