Penile Abscess Caused by Salmonella enteritidis Bacteraemia in an Adolescent with Newly Diagnosed Chronic-Phase Chronic Myeloid Leukaemia

Penile abscess is an uncommon urological infection, and isolation of Salmonella enteritidis from a penile abscess is exceptionally rare. Chronic myeloid leukaemia (CML) is a clonal myeloproliferative neoplasm driven by the BCR::ABL1 fusion gene. Most patients are diagnosed in chronic phase, and chronic-phase CML before intensive chemotherapy or progression to accelerated or blast phase should not be overinterpreted as a strong immunosuppressive condition predisposing directly to invasive bacterial infection. We report a microbiologically confirmed S. enteritidis penile abscess in an adolescent with newly diagnosed chronic-phase CML, most plausibly due to haematogenous seeding of locally inflamed or compromised genital tissue during bacteraemia.