Fournier's Gangrene Complicating Hematologic Malignancies: Literature Review and Treatment Suggestions

Giovanni D'Arena, Giuseppe Pietrantuono, Emilio Buccino, Giancarlo Pacifico, Pellegrino Musto
  • Giovanni D'Arena
    Hematology and Stem Cell Transplantation Unit, IRCCS Centro di Riferimento Oncologico della Basilicata, Rionero in Vulture (PZ), Italy | giovannidarena@libero.it
  • Giuseppe Pietrantuono
    Hematology and Stem Cell Transplantation Unit, IRCCS Centro di Riferimento Oncologico della Basilicata, Rionero in Vulture (PZ), Italy
  • Emilio Buccino
    Surgical Department, "S. Giovanni di Dio" Hospital, Melfi (Pz), Italy
  • Giancarlo Pacifico
    Surgical Department, "S. Giovanni di Dio" Hospital, Melfi (Pz), Italy
  • Pellegrino Musto
    Scientific Direction, IRCCS Centro di Riferimento Oncologico della Basilicata, Rionero in Vulture (PZ),

Abstract

Fournier’s gangrene (FG) is a rare but severe necrotizing fasciitis of the external genitalia that may complicate the clinical course of hematologic malignancies and sometimes may be the first sign of the disease. The clinical course of FG is very aggressive and the mortality is still high despite the improvement in its management. Early recognition of FG and prompt appropriate treatment with surgical debridement and administration of antibiotics are the cornerstone of the management of this very severe disease.

Keywords

Fournier; gangrene; malignancy; hematology

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Submitted: 2014-06-13 10:01:32
Published: 2013-11-04 00:00:00
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