EARLY AND LATE COMPLICATIONS RELATED TO CENTRAL VENOUS CATHETERS IN HAEMATOLOGICAL MALIGNANCIES: A RETROSPECTIVE ANALYSIS OF 1102 PATIENTS

Salvatore Giacomo Morano, Lorenzo Coppola, Roberto Latagliata, Paola Berneschi, Antonio Chistolini, Alessandra Micozzi, Corrado Girmenia, Massimo Breccia, Gregorio Brunetti, Angela Matturro, Giovanni Rosa, Pietro Guerrisi, Franco Mandelli, Roberto Foà, Giuliana Alimena
  • Salvatore Giacomo Morano
    Department of Cellular Biotechnology and Hematology ‘La Sapienza’ University Via Benevento 6, IT–00161 Rome (Italy), Italy | morano@bce.uniroma1.it
  • Lorenzo Coppola
    Hematology “AOU” Sassari, Italy, Italy
  • Roberto Latagliata
    Department of Cellular Biotechnology and Hematology ‘La Sapienza’ University Via Benevento 6, IT–00161 Rome (Italy), Italy
  • Paola Berneschi
    Department of Cellular Biotechnology and Hematology ‘La Sapienza’ University Via Benevento 6, IT–00161 Rome (Italy), Italy
  • Antonio Chistolini
    Department of Cellular Biotechnology and Hematology ‘La Sapienza’ University Via Benevento 6, IT–00161 Rome (Italy), Italy
  • Alessandra Micozzi
    Department of Cellular Biotechnology and Hematology ‘La Sapienza’ University Via Benevento 6, IT–00161 Rome (Italy), Italy
  • Corrado Girmenia
    Department of Cellular Biotechnology and Hematology ‘La Sapienza’ University Via Benevento 6, IT–00161 Rome (Italy), Italy
  • Massimo Breccia
    Department of Cellular Biotechnology and Hematology ‘La Sapienza’ University Via Benevento 6, IT–00161 Rome (Italy), Italy
  • Gregorio Brunetti
    Department of Cellular Biotechnology and Hematology ‘La Sapienza’ University Via Benevento 6, IT–00161 Rome (Italy), Italy
  • Angela Matturro
    Department of Cellular Biotechnology and Hematology ‘La Sapienza’ University Via Benevento 6, IT–00161 Rome (Italy), Italy
  • Giovanni Rosa
    Dipartimento Anestesia e Rianimazione, Azienda Policlinico Umberto I, "Sapienza" Università di Roma, Italy
  • Pietro Guerrisi
    Dipartimento Scienze Radiologiche, Azienda Policlinico Umberto I, "Sapienza" Università di Roma, Italy
  • Franco Mandelli
    Department of Cellular Biotechnology and Hematology ‘La Sapienza’ University Via Benevento 6, IT–00161 Rome (Italy), Italy
  • Roberto Foà
    Department of Cellular Biotechnology and Hematology ‘La Sapienza’ University Via Benevento 6, IT–00161 Rome (Italy), Italy
  • Giuliana Alimena
    Department of Cellular Biotechnology and Hematology ‘La Sapienza’ University Via Benevento 6, IT–00161 Rome (Italy), Italy

Abstract

Several severe complications may be associated with the use of central venous catheters (CVC). We retrospectively evaluated on a large cohort of patients the incidence of CVC-related early and late complications. From 7/99 to 12/2005, 1102 CVC have been implanted at our Institution in 881 patients with haematological malignancies (142,202 total day number of implanted CVC). Early mechanic complications were 79 (7.2% - 0.55/1,000 days/CVC). Thirty-nine episodes of early infective complications (<1 week from CVC implant) occurred (3.5% - 0.3/1000 days/CVC): furthermore, 187 episodes of CVC-related sepsis (17% - 1.3/1000 days/CVC) were recorded. There were 29 episodes (2.6%) of symptomatic CVC-related thrombotic complications, with a median interval from CVC implant of 60 days (range 7 – 395). The rate of CVC withdrawal due to CVC-related complications was 26%. The incidence of CVC-related complications in our series is in the range reported in the literature, notwithstanding cytopenia often coexisting in haematological patients.

Keywords

CVC, haematological malignancies, infections, thrombosis, cytopenia

Full Text:

PDF
HTML
Submitted: 2014-07-21 14:08:18
Published: 2014-02-18 00:00:00
Search for citations in Google Scholar
Related articles: Google Scholar
Abstract views:
189

Views:
PDF
170
HTML
768

Article Metrics

Metrics Loading ...

Metrics powered by PLOS ALM


Copyright (c) 2016 Mediterranean Journal of Hematology and Infectious Diseases

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

 

The Mediterranean Journal of Hematology and Infectious Diseases [eISSN 2035-3006] is owned by the U.C.S.C. and it is published by PAGEPress®, Pavia, Italy. All credits and honors to PKP for their OJS.
 
 
© PAGEPress 2008-2017     -     PAGEPress is a registered trademark property of PAGEPress srl, Italy.     -     VAT: IT02125780185