Marginal zone lymphomas have been associated with several infectious agents covering both viral and bacterial pathogens and in some cases a clear aetiological role has been established. Pathogenetic mechanisms are currently not completely understood, however the role of chronic stimulation of the host immune response with persistent lymphocyte activation represents the most convincing explanation for lymphoproliferation. Gastric MALT lymphoma is strictly associated with Helicobacter pylori infection and various eradicating protocols, developed due to increasing antibiotic resistance, represent the first line therapy. The response rate to eradication is good with 80% of response at 1 year; this finding is also noteworthy because recapitulates a cancer cured only by antibacterial approach and it satisfies the Koch postulates of causation, establishing a causative relationship between Hp and gastric MALT lymphoma. Patients with chronic HCV infection have 5 times higher risk to develop MZL, in particular an association with splenic and nodal MZL has been shown in several studies. Moreover, there is evidence of lymphoma regression after antiviral therapy with interferon+ribavirin, thus rising hope that new available drugs, extremely effective against HCV replication, could improve outcome also in HCV-driven lymphomas. The rare cases of MZL localized to orbital fat and eye conjunctivas have been associated with Chlamydia psittaci infection carried by birds. Efficacy of antibacterial therapy against C. psittaci are conflicting and generally poorer thain gastric MALT. Finally some case-reports will cover the relationship between primary cutaneous B-cell Lymphomas and Borrelia Burgdorferi.
Comments on this article
by paul hunter (2016-09-22)
by paul hunter (2016-09-22)
by katey martin (2016-10-21)
by Edina Clark (2016-11-09)
by Essay Campus Edina Clark (2016-12-01)
by Mr. Chris James (2017-01-17)
by Mr. Chris James (2017-01-17)
by sussan betcher (2017-02-24)
by Dete Moreira (2017-04-20)
by Beleza Sempre (2017-04-21)
by bela bela (2017-04-28)
by Beleza Sempre (2017-05-21)
by marcelo Santos (2017-05-25)
by marcelo Santos (2017-05-29)
by Miquelino Sanson (2017-06-02)
by an binh bot nghe (2017-06-15)
by bela bela (2017-06-26)
by bela bela (2017-07-02)
by agen agen judi online (2017-07-18)
by Mr. Stephen Brian (2017-07-19)
by Roger Jack (2017-07-21)
by An Bình Bột Nghệ (2017-07-23)
by hillary davidson (2017-07-28)
by maria kim (2017-07-28)
by Adam Milne (2017-08-08)
by luisa mendes (2017-08-11)
by Geyser Ecotar Nano (2017-08-19)
by toko jual obat klg (2017-08-25)
by Robert Gere (2017-08-31)
by bela bela (2017-09-03)
by Hugo Lopes (2017-09-08)
by jadisukses3 jadisukses3 jadisukses3 jadisukses3 (2017-10-01)
by Hugo Lopes (2017-10-09)
by Hugo Lopes (2017-10-09)
by Nguyễn Hà Chi Nguyễn Hà Chi (2017-10-25)
by Antonio Silva Silva (2017-11-08)
by Jake Jake Fuller (2017-11-18)
by Jake Jake Fuller (2017-11-18)
by Mr Rain Both (2017-11-26)
by Catherine Denvers (2017-12-05)
by Zenny Disuja (2017-12-06)
by Mr Edward Myers (2017-12-07)
by Kathy Kris (2017-12-13)
by Eyman Shanon (2017-12-14)
by Millsaps Annamaria (2017-12-14)
by Brumbaugh Rees (2017-12-14)
by Rali Raj (2017-12-17)
by Treva Ladawn (2017-12-18)
by Zoho John (2017-12-18)
by Gannon Keith (2017-12-18)
by Vance Matsuda (2017-12-19)
by Demaris Johnette (2017-12-19)
by Duong Vat Gia Re (2017-12-19)
by Star Lehto (2017-12-21)
by Keith Nickie (2017-12-21)
by Schechter Maclean (2017-12-21)
by Terresa Lasonya (2017-12-22)
by Gregoria Mitchel (2017-12-22)
by Zilu Raj (2017-12-23)
by Mantooth Barnes (2017-12-25)
by Zilu Raj (2017-12-27)
by Keva Lucilla (2017-12-27)
by Stanton Shane (2017-12-28)
by Gannon Nies (2017-12-28)
by Donald Maxima (2017-12-28)
by Barnes Brevard (2017-12-29)
by Kirk Kilby (2017-12-29)
by Enciso Cooley (2017-12-30)
by Grisel Ruben (2017-12-30)
by Rosalee Mae (2018-01-01)
by James Moore (2018-01-04)
by Molly Preston (2018-01-06)
by Dolores Sadie (2018-01-14)
by شركة نقل اثاث بالرياض haytham ALI ali (2018-01-17)
by Garrigan Tammi (2018-01-18)
by Nickie Donald (2018-01-19)
by Donald Hession (2018-01-20)
by Stanton Gregoria (2018-01-26)
by Luu Brooks (2018-01-28)
by Carl Holley (2018-01-28)
by Genoveva Aquilino (2018-01-30)
by Andrade Donald (2018-01-31)
by Genoveva Daphne (2018-02-02)
by Kierstead Ruben (2018-02-04)
by Roseline Ruland (2018-02-04)
by Jauregui Lehto (2018-02-05)
by Adell Gannon (2018-02-05)
by Cory Sadie (2018-02-05)
by Lemon Gannon (2018-02-06)
by Arrieta Sumiko (2018-02-06)
by Lance Edington (2018-02-07)
by Nora jones (2018-02-09)
by Vietnamvisa Agency (2018-02-10)
by Cline Cuomo (2018-02-12)
by Mantooth Tressa (2018-02-14)
by Gisele Star (2018-02-15)
by Genoveva Kirk (2018-02-17)
by Allie Terrazas (2018-02-17)
by Cuomo Donovan (2018-02-19)
by Stanton Willis (2018-02-21)
by Rosena Gannon (2018-02-21)
by haiwon soon (2018-02-22)
by Benner Emanuel (2018-02-24)
by Kilby Tammi (2018-02-25)
by Terresa Jennell (2018-02-25)
by Mariko Nelia (2018-02-26)
by Krieger Edgar (2018-02-27)
by Janita Atchley (2018-02-27)
by Racquel Norsworthy (2018-02-27)
by Carrera Shawnna (2018-02-28)
by Enciso Barnes (2018-03-01)
by Donald Lawver (2018-03-02)
by Bev Earwood (2018-03-02)
by Lucilla Benner (2018-03-03)
by Grisel Lawver (2018-03-03)
by Genoveva Maribeth (2018-03-03)
by Vandermolen Brevard (2018-03-04)
by Schechter Dematteo (2018-03-04)
by Natashia Roseline (2018-03-05)
by Roxann Brooke (2018-03-05)
by Miquelino Sanson (2018-03-05)
by Maxima Siegal (2018-03-05)
by Tocco Ruland (2018-03-05)
by Earwood Atchley (2018-03-06)
by Cesar Shanon (2018-03-08)
by wesleylima lima (2018-03-08)
by wesleylima lima (2018-03-08)
by wesleylima lima (2018-03-08)
by wesleylima lima (2018-03-08)
by wesleylima lima (2018-03-08)
by wesleylima lima (2018-03-08)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by wesleylima lima (2018-03-09)
by masykur hasyim (2018-03-09)
by Rusk Eyman (2018-03-09)
by Johnette Louetta (2018-03-10)
by Donovan Mitchell (2018-03-11)
by Leonida Esperanza (2018-03-12)
by Mr Lắp đặt mạng internet FPT FPT Telecom (2018-03-15)
by Leonida Holley (2018-03-15)
by Esperanza Holley (2018-03-15)
by Esperanza Tusing (2018-03-16)
by Lemon Delorse (2018-03-16)
by Nurse Keva (2018-03-16)
by Jame Smith (2018-03-16)
by Johnette Johnette (2018-03-17)
by Mitchel Aichele (2018-03-18)
by Holley Korn (2018-03-19)
by erik Erik erik Rodrigues (2018-03-20)
by Trezza Shanon (2018-03-21)
by nhiem vu (2018-03-21)
by Lando Kirk (2018-03-21)
by Gannon Nickie (2018-03-22)
by Carina Esterly (2018-03-23)
by Miquelino Sanson (2018-03-23)
by Mariko Kiara (2018-03-23)
by Cassi Trapani (2018-03-25)
by Miquelino Sanson (2018-03-26)
by Johnathan Avelina (2018-03-26)
by Kinnaird Esperanza (2018-03-27)
by Lance Shofner (2018-03-27)
by Nicholls Sadie (2018-03-27)
by Livers Stanton (2018-03-27)
by Eyman Roseline (2018-03-27)
by Maclean Gannon (2018-03-28)
by Valencia Jiles (2018-03-28)
by Allie Cataldo (2018-03-28)
by Benner Ladawn (2018-03-28)
by Lezlie Arrieta (2018-03-29)
by Babette Maxima (2018-03-29)
by Johnette Tocco (2018-03-29)
by Mcnicholas Livers (2018-03-29)
by Cuomo Lucilla (2018-03-29)
by Enciso Cline (2018-03-30)
by Gale Gigi (2018-03-30)
by Miguel Barcelo (2018-03-30)
by Emanuel Allyson (2018-03-31)
by Neal Neal (2018-03-31)
by Lynsey Esperanza (2018-03-31)
by Cesar Roxann (2018-04-01)
by Ritchie Star (2018-04-01)
by Pedro Silva (2018-04-01)
by January Gale (2018-04-02)
by Rosena Arrieta (2018-04-02)
by Seegmiller Cuomo (2018-04-03)
by Freyer Trezza (2018-04-03)
by Vernita Daphne (2018-04-03)
by Aichele Holley (2018-04-04)
by Nies Jolliff (2018-04-05)
by Rafaela Cristina (2018-04-05)
by Freyer Aquilino (2018-04-07)
by Maria Paulina Souza (2018-04-07)
by denise abreu (2018-04-07)
by Carrera Leonida (2018-04-08)
Anonymous User (2018-04-09)
by Bird Larsen (2018-04-09)
by cintia Dias (2018-04-09)
by Renato Gonzaga (2018-04-09)
by negocioslocaisweb@gmail.com negocioslocaisweb@gmail.com (2018-04-10)
by daniel gonalo (2018-04-10)
by Marcone Gonçalves (2018-04-10)
by Bethinha Souza (2018-04-11)
by lena marques (2018-04-11)
by denise abreu (2018-04-11)
by Miquelino Sanson (2018-04-12)
by Lance Jenelle (2018-04-13)
by Terresa Nurse (2018-04-14)
by Tammi Bird (2018-04-14)
by January Azar (2018-04-14)
by Miquelino Sanson (2018-04-16)
by Carl Lawver (2018-04-16)
by Terresa Groman (2018-04-17)
by Donald Andrade (2018-04-17)
by Brooke Roland (2018-04-17)
by Renea Maxima (2018-04-17)
by Nicholls Sanjuana (2018-04-17)
by Miquelino Sanson (2018-04-18)
by Miquelino Sanson (2018-04-19)
by Fredda Kiara (2018-04-20)
by Miquelino Sanson (2018-04-20)