ZIKA VIRUS: A REVIEW FROM THE VIRUS BASICS TO PROPOSED MANAGEMENT STRATEGIES

Lorenzo Zammarchi, Michele Spinicci, Michele Spinicci, Alessandro Bartoloni, Alessandro Bartoloni
  • Lorenzo Zammarchi
    Affiliation not present
  • Michele Spinicci
    Affiliation not present
  • Michele Spinicci
    Affiliation not present
  • Alessandro Bartoloni
    Affiliation not present

Abstract

This review aims to summarize the body of knowledge available on Zika virus to date. A comprehensive review of the scientific literature on Zika virus was performed with the aim to stress relevant aspects for healthcare professionals in non-endemic area. For several years, the Zika virus infection was considered an extremely rare exotic disease with poor clinical relevance. However, Zika virus has recently gained the attention of the scientific community and public opinion since the virus spread to the Pacific islands and the South America in an unprecedented epidemic, and additionally due to the definitive evidence that the infection could be complicated by Guillain-Barré syndrome, passed through vertical transmission, and result in central nervous system abnormalities (including microcephaly) of the fetus. Studies and scientific evidences on the complications associated with Zika virus infection are growing day by day. It is advisable that the healthcare professionals working in non-endemic areas maintain full awareness on this issue in order to practice proper management of the imported cases of Zika virus infection.

Keywords

Zika virus, pregnancy, microcephaly, Guillain Barré, arbovirus

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Published: 2016-11-01 00:00:00
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References

References

Weaver SC, Costa F, Garcia-Blanco MA, Ko AI, Ribeiro GS, Saade G, Shi PY, Vasilakis N: Zika virus: History, emergence, biology, and prospects for control. Antiviral research 2016, 130:69-80.

Faye O, Freire CC, Iamarino A, de Oliveira JV, Diallo M, Zanotto PM, Sall AA: Molecular evolution of Zika virus during its emergence in the 20(th) century. PLoS neglected tropical diseases 2014, 8(1):e2636.

Anderson KB, Thomas SJ, Endy TP: The Emergence of Zika Virus: A Narrative Review. Annals of internal medicine 2016.

Diallo D, Sall AA, Diagne CT, Faye O, Ba Y, Hanley KA, Buenemann M, Weaver SC, Diallo M: Zika virus emergence in mosquitoes in southeastern Senegal, 2011. PloS one 2014, 9(10):e109442.

Ledermann JP, Guillaumot L, Yug L, Saweyog SC, Tided M, Machieng P, Pretrick M, Marfel M, Griggs A, Bel M et al: Aedes hensilli as a potential vector of Chikungunya and Zika viruses. PLoS neglected tropical diseases 2014, 8(10):e3188.

Musso D, Nilles EJ, Cao-Lormeau VM: Rapid spread of emerging Zika virus in the Pacific area. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2014, 20(10):O595-596.

Wong PS, Li MZ, Chong CS, Ng LC, Tan CH: Aedes (Stegomyia) albopictus (Skuse): a potential vector of Zika virus in Singapore. PLoS neglected tropical diseases 2013, 7(8):e2348.

Di Luca M, Severini F, Toma L, Boccolini D, Romi R, Remoli ME, Sabbatucci M, Rizzo C, Venturi G, Rezza G et al: Experimental studies of susceptibility of Italian Aedes albopictus to Zika virus. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2016, 21(18).

Chouin-Carneiro T, Vega-Rua A, Vazeille M, Yebakima A, Girod R, Goindin D, Dupont-Rouzeyrol M, Lourenco-de-Oliveira R, Failloux AB: Differential Susceptibilities of Aedes aegypti and Aedes albopictus from the Americas to Zika Virus. PLoS neglected tropical diseases 2016,

(3):e0004543.

Grard G, Caron M, Mombo IM, Nkoghe D, Mboui Ondo S, Jiolle D, Fontenille D, Paupy C, Leroy EM: Zika virus in Gabon (Central Africa)--2007: a new threat from Aedes albopictus? PLoS neglected tropical diseases 2014, 8(2):e2681.

Besnard M, Lastere S, Teissier A, Cao-Lormeau V, Musso D: Evidence of perinatal transmission of Zika virus, French Polynesia, December 2013 and February 2014. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2014, 19(13).

Calvet G, Aguiar RS, Melo AS, Sampaio SA, de Filippis I, Fabri A, Araujo ES, de Sequeira PC, de Mendonca MC, de Oliveira L et al: Detection and sequencing of Zika virus from amniotic fluid of fetuses with microcephaly in Brazil: a case study. The Lancet Infectious diseases 2016.

Mlakar J, Korva M, Tul N, Popovic M, Poljsak-Prijatelj M, Mraz J, Kolenc M, Resman Rus K, Vesnaver Vipotnik T, Fabjan Vodusek V et al: Zika Virus Associated with Microcephaly. The New England journal of medicine 2016, 374(10):951-958.

Venturi G, Zammarchi L, Fortuna C, Remoli ME, Benedetti E, Fiorentini C, Trotta M, Rizzo C, Mantella A, Rezza G et al: An autochthonous case of Zika due to possible sexual transmission, Florence, Italy, 2014. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2016, 21(8).

Deckard DT, Chung WM, Brooks JT, Smith JC, Woldai S, Hennessey M, Kwit N, Mead P: Male-to-Male Sexual Transmission of Zika Virus - Texas, January 2016. MMWR Morbidity and mortality weekly report 2016, 65(14):372-374.

Fréour T, Mirallié S, Hubert B, Splingart C, Barrière P, Maquart M, Leparc-Goffart I: Sexual transmission of Zika virus in an entirely asymptomatic couple returning from a Zika epidemic area, France, April 2016. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2016, 21(23).

Nicastri E, Castilletti C, Liuzzi G, Iannetta M, Capobianchi M, Ippolito G: Persistent detection of Zika virus RNA in semen for six months after symptom onset in a traveller returning from Haiti to Italy, February 2016. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2016, 21(32):pii=30314. DOI: http://dx.doi.org/10.2807/1560-7917.ES.2016.21.32.30314.

Davidson A, Slavinski S, Komoto K, Rakeman J, Weiss D: Suspected Female-to-Male Sexual Transmission of Zika Virus - New York City, 2016. MMWR Morbidity and mortality weekly report 2016, 65(28):716-717.

Prisant N, Bujan L, Benichou H, Hayot PH, Pavili L, Lurel S, Herrmann C, Janky E, Joguet G: Zika virus in the female genital tract. The Lancet Infectious diseases 2016.

Musso D, Nhan T, Robin E, Roche C, Bierlaire D, Zisou K, Shan Yan A, Cao-Lormeau VM, Broult J: Potential for Zika virus transmission through blood transfusion demonstrated during an outbreak in French Polynesia, November 2013 to February 2014. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2014, 19(14).

Filipe AR, Martins CM, Rocha H: Laboratory infection with Zika virus after vaccination against yellow fever. Archiv fur die gesamte Virusforschung 1973, 43(4):315-319.

Leung GH, Baird RW, Druce J, Anstey NM: ZIKA VIRUS INFECTION IN AUSTRALIA FOLLOWING A MONKEY BITE IN INDONESIA. The Southeast Asian journal of tropical medicine and public health 2015, 46(3):460-464.

Dupont-Rouzeyrol M, Biron A, O'Connor O, Huguon E, Descloux E: Infectious Zika viral particles in breastmilk. Lancet (London, England) 2016, 387(10023):1051.

Barzon L, Pacenti M, Berto A, Sinigaglia A, Franchin E, Lavezzo E, Brugnaro P, Palu G: Isolation of infectious Zika virus from saliva and prolonged viral RNA shedding in a traveller returning from the Dominican Republic to Italy, January 2016. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2016, 21(10).

Musso D, Roche C, Robin E, Nhan T, Teissier A, Cao-Lormeau VM: Potential sexual transmission of Zika virus. Emerging infectious diseases 2015, 21(2):359-361.

Roze B, Najioullah F, Ferge JL, Apetse K, Brouste Y, Cesaire R, Fagour C, Fagour L, Hochedez P, Jeannin S et al: Zika virus detection in urine from patients with Guillain-Barre syndrome on Martinique, January 2016. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2016, 21(9).

Dick GW, Kitchen SF, Haddow AJ: Zika virus. I. Isolations and serological specificity. Transactions of the Royal Society of Tropical Medicine and Hygiene 1952, 46(5):509-520.

Macnamara FN: Zika virus: a report on three cases of human infection during an epidemic of jaundice in Nigeria. Transactions of the Royal Society of Tropical Medicine and Hygiene 1954, 48(2):139-145.

Plourde AR, Bloch EM: A Literature Review of Zika Virus. Emerging infectious diseases 2016, 22(7).

Mallet H, Vial A, Musso D: Bilan de l’épidémie à virus Zika en Polynésie Française 2013-2014. Bulletin d’information sanitaires, épidémiologiques et statistiques 2015.

Lanciotti RS, Kosoy OL, Laven JJ, Velez JO, Lambert AJ, Johnson AJ, Stanfield SM, Duffy MR: Genetic and serologic properties of Zika virus associated with an epidemic, Yap State, Micronesia, 2007. Emerging infectious diseases 2008, 14(8):1232-1239.

Zanluca C, Melo VC, Mosimann AL, Santos GI, Santos CN, Luz K: First report of autochthonous transmission of Zika virus in Brazil. Memorias do Instituto Oswaldo Cruz 2015, 110(4):569-572.

Zammarchi L, Tappe D, Fortuna C, Remoli ME, Gunther S, Venturi G, Bartoloni A, Schmidt-Chanasit J: Zika virus infection in a traveller returning to Europe from Brazil, March 2015. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2015, 20(23).

Zika virus infection: global update on epidemiology and potentially associated clinical manifestations. Releve epidemiologique hebdomadaire / Section d'hygiene du Secretariat de la Societe des Nations = Weekly epidemiological record / Health Section of the Secretariat of the League of Nations 2016, 91(7):73-81.

World Helath Organization: Situation Report. Zika virus, Microcephaly, Guillain Barré Syndrome, May 26, 2016. 2016.

European Centre for Disease Prevention and Control: Zika virus disease epidemic. Rapid Risk Assessment. Seventh update. 8 July 2016. ECDC 2016.

McCarthy M: Four in Florida are infected with Zika from local mosquitoes. BMJ (Clinical research ed) 2016, 354:i4235.

Duffy MR, Chen TH, Hancock WT, Powers AM, Kool JL, Lanciotti RS, Pretrick M, Marfel M, Holzbauer S, Dubray C et al: Zika virus outbreak on Yap Island, Federated States of Micronesia. The New England journal of medicine 2009, 360(24):2536-2543.

Lessler J, Ott C, Carcelen A, Konikoff J, Williamson J, Bi Q, Kucirka L, Cummings D, Reichd N, Chaisson L: Times to key events in the course of Zika infection and their implications: a systematic review and pooled analysis. Bull World Health Organ 2016.

European Centre for Disease Prevention and Control: Proposed case definition for surveillance of Zika virus infection. ECDC Web Site 2016.

Waddell LA, Greig JD: Scoping Review of the Zika Virus Literature. PloS one 2016, 11(5):e0156376.

Adibi JJ, Marques ET, Jr., Cartus A, Beigi RH: Teratogenic effects of the Zika virus and the role of the placenta. Lancet (London, England) 2016, 387(10027):1587-1590.

Lazear HM, Govero J, Smith AM, Platt DJ, Fernandez E, Miner JJ, Diamond MS: A Mouse Model of Zika Virus Pathogenesis. Cell host & microbe 2016, 19(5):720-730.

Cugola FR, Fernandes IR, Russo FB, Freitas BC, Dias JL, Guimaraes KP, Benazzato C, Almeida N, Pignatari GC, Romero S et al: The Brazilian Zika virus strain causes birth defects in experimental models. Nature 2016, 534(7606):267-271.

Li C, Xu D, Ye Q, Hong S, Jiang Y, Liu X, Zhang N, Shi L, Qin CF, Xu Z: Zika Virus Disrupts Neural Progenitor Development and Leads to Microcephaly in Mice. Cell stem cell 2016.

Miner JJ, Cao B, Govero J, Smith AM, Fernandez E, Cabrera OH, Garber C, Noll M, Klein RS, Noguchi KK et al: Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise. Cell 2016, 165(5):1081-1091.

Tappe D, Perez-Giron JV, Zammarchi L, Rissland J, Ferreira DF, Jaenisch T, Gomez-Medina S, Gunther S, Bartoloni A, Munoz-Fontela C et al: Cytokine kinetics of Zika virus-infected patients from acute to reconvalescent phase. Medical microbiology and immunology 2016, 205(3):269-273.

Cao-Lormeau VM, Blake A, Mons S, Lastere S, Roche C, Vanhomwegen J, Dub T, Baudouin L, Teissier A, Larre P et al: Guillain-Barre Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study. Lancet (London, England) 2016, 387(10027):1531-1539.

World Health Organization: Situation Report. Zika virus, Microcephaly and Guillain-Barré syndrome. 1 June 2016. 2016.

World Health Organization: Guillain-Barré syndrome – Brazil. Disease Outbreak News. 8 February 2016. World Health Organization website: http://wwwwhoint/csr/don/8-february-2016-gbs-brazil/en/ consulted on June 12, 2016 2016.

Kleber de Oliveira W, Cortez-Escalante J, De Oliveira WT, do Carmo GM, Henriques CM, Coelho GE, Araujo de Franca GV: Increase in Reported Prevalence of Microcephaly in Infants Born to Women Living in Areas with Confirmed Zika Virus Transmission During the First Trimester of Pregnancy - Brazil, 2015. MMWR Morbidity and mortality weekly report 2016, 65(9):242-247.

Oliveira Melo AS, Malinger G, Ximenes R, Szejnfeld PO, Alves Sampaio S, Bispo de Filippis AM: Zika virus intrauterine infection causes fetal brain abnormality and microcephaly: tip of the iceberg? Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2016, 47(1):6-7.

CDC: Recognizing, managing, and reporting Zika virus infections in travelers returning from Central America, South America, the Caribbean, and Mexico. CDC Health Advisory Atlanta, GA: US Department of Health and Human Services, CDC 2016.

European Centre for Disease Prevention and Control: Rapid risk assessment: microcephaly in Brazil potentially linked to the Zika virus epidemic. 2015.

WHO: Director-General summarizes the outcome of the Emergency Committee regarding clusters of microcephaly and Guillain-Barré syndrome. 2016.

Johansson MA, Mier YT-RL, Reefhuis J, Gilboa SM, Hills SL: Zika and the Risk of Microcephaly. The New England journal of medicine 2016.

Brasil P, Pereira JP, Jr., Raja Gabaglia C, Damasceno L, Wakimoto M, Ribeiro Nogueira RM, Carvalho de Sequeira P, Machado Siqueira A, Abreu de Carvalho LM, Cotrim da Cunha D et al: Zika Virus Infection in Pregnant Women in Rio de Janeiro - Preliminary Report. The New England journal of medicine 2016.

Hazin AN, Poretti A, Turchi Martelli CM, Huisman TA, Di Cavalcanti Souza Cruz D, Tenorio M, van der Linden A, Pena LJ, Brito C, Gil LH et al: Computed Tomographic Findings in Microcephaly Associated with Zika Virus. The New England journal of medicine 2016, 374(22):2193-2195.

de Paula Freitas B, de Oliveira Dias JR, Prazeres J, Sacramento GA, Ko AI, Maia M, Belfort R, Jr.: Ocular Findings in Infants With Microcephaly Associated With Presumed Zika Virus Congenital Infection in Salvador, Brazil. JAMA ophthalmology 2016.

Carteaux G, Maquart M, Bedet A, Contou D, Brugieres P, Fourati S, Cleret de Langavant L, de Broucker T, Brun-Buisson C, Leparc-Goffart I et al: Zika Virus Associated with Meningoencephalitis. The New England journal of medicine 2016, 374(16):1595-1596.

Mecharles S, Herrmann C, Poullain P, Tran TH, Deschamps N, Mathon G, Landais A, Breurec S, Lannuzel A: Acute myelitis due to Zika virus infection. Lancet (London, England) 2016, 387(10026):1481.

Roze B, Najioullah F, Signate A, Apetse K, Brouste Y, Gourgoudou S, Fagour L, Abel S, Hochedez P, Cesaire R et al: Zika virus detection in cerebrospinal fluid from two patients with encephalopathy, Martinique, February 2016. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2016, 21(16).

Arzuza-Ortega L, Polo A, Perez-Tatis G, Lopez-Garcia H, Parra E, Pardo-Herrera LC, Rico-Turca AM, Villamil-Gomez W, Rodriguez-Morales AJ: Fatal Sickle Cell Disease and Zika Virus Infection in Girl from Colombia. Emerging infectious diseases 2016, 22(5):925-927.

Pan American Health Organization, World Health Organization: Epidemiological alert. Neurological syndrome, congenital malformations, and Zika virus infection. Implications for public health in the Americas. 2015 2015.

Zammarchi L, Stella G, Mantella A, Bartolozzi D, Tappe D, Gunther S, Oestereich L, Cadar D, Munoz-Fontela C, Bartoloni A et al: Zika virus infections imported to Italy: clinical, immunological and virological findings, and public health implications. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2015, 63:32-35.

Venturi G, Zammarchi L, Fortuna C, Remoli ME, Benedetti E, Fiorentini C, Trotta M, Rizzo C, Mantella A, Rezza G et al: Authors' reply: diagnostic challenges to be considered regarding Zika virus in the context of the presence of the vector Aedes albopictus in Europe. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2016, 21(10).

Johnson BW, Kosoy O, Martin DA, Noga AJ, Russell BJ, Johnson AA, Petersen LR: West Nile virus infection and serologic response among persons previously vaccinated against yellow fever and Japanese encephalitis viruses. Vector borne and zoonotic diseases (Larchmont, NY) 2005, 5(2):137-145.

Huzly D, Hanselmann I, Schmidt-Chanasit J, Panning M: High specificity of a novel Zika virus ELISA in European patients after exposure to different flaviviruses. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2016, 21(16).

European Centre for Disease Prevention and Control: Interim guidance for healthcare providers and Zika virus laboratory diagnosis. ECDC TECHNICAL DOCUMENT 2016.

Gourinat AC, O'Connor O, Calvez E, Goarant C, Dupont-Rouzeyrol M: Detection of Zika virus in urine. Emerging infectious diseases 2015, 21(1):84-86.

Lustig Y, Mendelson E, Paran N, Melamed S, Schwartz E: Detection of Zika virus RNA in whole blood of imported Zika virus disease cases up to 2 months after symptom onset, Israel, December 2015 to April 2016. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2016, 21(26).

Driggers RW, Ho CY, Korhonen EM, Kuivanen S, Jaaskelainen AJ, Smura T, Rosenberg A, Hill DA, DeBiasi RL, Vezina G et al: Zika Virus Infection with Prolonged Maternal Viremia and Fetal Brain Abnormalities. The New England journal of medicine 2016, 374(22):2142-2151.

Baud D, Van Mieghem T, Musso D, Truttmann AC, Panchaud A, Vouga M: Clinical management of pregnant women exposed to Zika virus. The Lancet Infectious diseases 2016.

Centers for Disease Control and Prevention: Guidelines for Travelers Visiting Friends and Family in Areas with Chikungunya, Dengue, or Zika. CDC Web site Consulted on August 7, 2016 Available at: http://wwwnccdcgov/travel/page/guidelines-vfr-chikungunya-dengue-zika 2016.

Oduyebo T, Igbinosa I, Petersen EE, Polen KN, Pillai SK, Ailes EC, Villanueva JM, Newsome K, Fischer M, Gupta PM et al: Update: Interim Guidance for Health Care Providers Caring for Pregnant Women with Possible Zika Virus Exposure - United States, July 2016. MMWR Morbidity and mortality weekly report 2016, 65(29):739-744.

Bocanegra C, Sulleiro E, Soriano-Arandes A, Pou D, Suy A, Llurba E, Rodo C, Espasa M, Campins M, Martin A et al: Zika virus infection in pregnant women in Barcelona, Spain. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2016.

Ministero della Salute: Piano Nazionale di sorveglianza e risposta alle arbovirosi trasmesse da zanzare (Aedes sp.) con particolare riferimento a virus Chikungunya, Dengue e virus Zika - 2016. Circolare 0017200-16/06/2016-DGPRE-DGPRE-P Available at: http://wwwtrovanormesalutegovit/norme/renderNormsanPdf;jsessionid=TR1zmYYqgDn9E34D+9A4yg__sgc3-prd-sal?anno=2016&codLeg=55229&parte=1%20&serie=null Consulted on August 8, 2016 2016.

Fleming-Dutra KE, Nelson JM, Fischer M, Staples JE, Karwowski MP, Mead P, Villanueva J, Renquist CM, Minta AA, Jamieson DJ et al: Update: Interim Guidelines for Health Care Providers Caring for Infants and Children with Possible Zika Virus Infection--United States, February 2016. MMWR Morbidity and mortality weekly report 2016, 65(7):182-187.

Larocca RA, Abbink P, Peron JP, Zanotto PM, Iampietro MJ, Badamchi-Zadeh A, Boyd M, Ng'ang'a D, Kirilova M, Nityanandam R et al: Vaccine protection against Zika virus from Brazil. Nature 2016.

Martins KA, Dye JM, Bavari S: Considerations for the development of Zika virus vaccines. Vaccine 2016, 34(33):3711-3712.

Medlock JM, Hansford KM, Versteirt V, Cull B, Kampen H, Fontenille D, Hendrickx G, Zeller H, Van Bortel W, Schaffner F: An entomological review of invasive mosquitoes in Europe. Bulletin of entomological research 2015, 105(6):637-663.

Gjenero-Margan I, Aleraj B, Krajcar D, Lesnikar V, Klobucar A, Pem-Novosel I, Kurecic-Filipovic S, Komparak S, Martic R, Duricic S et al: Autochthonous dengue fever in Croatia, August-September 2010. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2011, 16(9).

Succo T, Leparc-Goffart I, Ferre JB, Roiz D, Broche B, Maquart M, Noel H, Catelinois O, Entezam F, Caire D et al: Autochthonous dengue outbreak in Nimes, South of France, July to September 2015. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2016, 21(21).

Marchand E, Prat C, Jeannin C, Lafont E, Bergmann T, Flusin O, Rizzi J, Roux N, Busso V, Deniau J et al: Autochthonous case of dengue in France, October 2013. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2013, 18(50):20661.

La Ruche G, Souares Y, Armengaud A, Peloux-Petiot F, Delaunay P, Despres P, Lenglet A, Jourdain F, Leparc-Goffart I, Charlet F et al: First two autochthonous dengue virus infections in metropolitan France, September 2010. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2010, 15(39):19676.

Rezza G, Nicoletti L, Angelini R, Romi R, Finarelli AC, Panning M, Cordioli P, Fortuna C, Boros S, Magurano F et al: Infection with chikungunya virus in Italy: an outbreak in a temperate region. Lancet (London, England) 2007, 370(9602):1840-1846.

Delisle E, Rousseau C, Broche B, Leparc-Goffart I, L'Ambert G, Cochet A, Prat C, Foulongne V, Ferre JB, Catelinois O et al: Chikungunya outbreak in Montpellier, France, September to October 2014. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2015, 20(17).

Outbreak news. Chikungunya, Spain. Releve epidemiologique hebdomadaire / Section d'hygiene du Secretariat de la Societe des Nations = Weekly epidemiological record / Health Section of the Secretariat of the League of Nations 2015, 90(33):409.

European Centre for Disease Prevention and Control: Zika virus disease epidemic: Preparedness planning guide for diseases transmitted by Aedes aegypti and Aedes albopictus. ECDC 2016.

Petersen EE, Polen KN, Meaney-Delman D, Ellington SR, Oduyebo T, Cohn A, Oster AM, Russell K, Kawwass JF, Karwowski MP et al: Update: Interim Guidance for Health Care Providers Caring for Women of Reproductive Age with Possible Zika Virus Exposure - United States, 2016. MMWR Morbidity and mortality weekly report 2016, 65(12):315-322.

World Health Organization: Prevention of sexual transmission of Zika virus Interim guidance update 7 June 2016. WHO/ZIKV/MOC/161 Rev2 2016.

European Centre for Disease Prevention and Control: Zika virus and safety of substances of human origin - A guide for preparedness activities in Europe. . ECDC 2016.

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