Scientific Letters
Vol. 9 No. 1 (2017): Review, Original Articles, Case Reports
Respiratory function in pediatric African SCA patients underwent bone marrow transplantation
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Received: January 8, 2017
Accepted: March 14, 2017
Accepted: March 14, 2017
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Hematology
Authors
Children with sickle cell anemia (SCA) are prone to invasive infections caused by S. pneumonia, H. influenzae, and Plasmodium falciparum. The presence of asthma increases the risk of mortality, and it has been shown an association between the presence of bronchial hyperactivity and the onset of acute chest syndrome. Like thalassemia, allogeneic hematopoietic stem cell transplantation (HSCT) is curative in most individuals with SCA. We report pulmonary function analyzed by spirometry, before and after transplantation, in a group of Nigerian SCA children. Our results indicate that restrictive pulmonary pattern (RVP) is a common finding in these patients. Although we do not observe significant improvements in lung function after 3-6 months of transplantation, it is useful to perform a spirometric evaluation of these patients at the time of transplant.
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“Respiratory function in pediatric African SCA patients underwent bone marrow transplantation” (2017) Mediterranean Journal of Hematology and Infectious Diseases, 9(1), p. e2017030. doi:10.4084/mjhid.2017.030.
