Fascioliasis: a not rare cause of hypereosinophilia in developing countries, present in developed too

Gülali Aktaş, İsmail Necati Hakyemez, Abdülkadir Küçükbayrak, Safiye Gürel, Tekin Taş
  • Gülali Aktaş
    Abant Izzet Baysal University Hospital, Department of Internal Medicine, Turkey
  • Abdülkadir Küçükbayrak
    Abant Izzet Baysal University Hospital, Turkey
  • Safiye Gürel
    Abant Izzet Baysal University Hospital, Turkey
  • Tekin Taş
    Abant Izzet Baysal University Hospital, Turkey


Fascioliasis, which is a worlwide parasitic zoonosis,endemic in south-est mediterranean areas, but uncommon in other areas. Clinical signs are usually non-specific. A 32 year old male patient was admitted to our hospital with complaints of abdominal pain, diarrhea, fatigue, nausea, lost of apetite, itching, cough, night sweats and weight loss. Complete blood count revealed hypereosinophilia. The abdominal ultrasound scan was normal. But computed tomography scan revealed irregular nodular lesions in periportal area of the liver. Based on these clinical and radiological signs and continuous hypereosinophilia, the patient was serologically investigated for Fasciola hepatica infection. F. hepatica indirect hemagglutination test in serum was positive at a titer of 1/1280. Single dose Triclabendasole 10mg/kg was administered and repeated two weeks later. Clinical and laboratory signs were completely resolved after treatment.  Serological tests for fascioliasis should be included in all patients with  hypereosinophilia and abnormal liver CT.


hypereosinophilia, fascioliasis, parasitic infections

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Submitted: 2014-06-13 09:34:36
Published: 2012-05-06 00:00:00
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