Sickle cell disease and Bartonella spp. infection

Main Article Content

Paulo Eduardo Neves Ferreira Velho *
Marna Elise Ericson
David Mair
Kalpna Gupta
(*) Corresponding Author:
Paulo Eduardo Neves Ferreira Velho | penfvelho@gmail.com

Abstract

Sickle cell disease is the most common hereditary hematologic disorder in the world. Painful vaso-occlusive crises are the hallmark of the disease and it is difficult to treat. Chronic infection is related to a higher painful crisis rate in these patients. Bartonella spp. are fastidious bacteria of zoonotic transmission. They can cause human asymptomatic infection as well as fatal outcome. Pain, fatigue and fever, characteristic features of Bartonella spp. infection are manifest in sickle cell disease patients. Bartonella spp. infection should be ruled in sickle cell disease patients.


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Author Biographies

Paulo Eduardo Neves Ferreira Velho, University of Campinas / University of Minnesota

MD, PhDAssistant Professor of the Division of Dermatology, Department of Medicine, University of Campinas / UNICAMP, Brazil and Research Associate of the Department of Dermatology, University of Minnesota, USA 

Marna Elise Ericson, University of Minnesota, USA

PhDAssistant Professor of the Department of Dermatology / Center for Drug Design

David Mair, American Red-Cross-North Central Region

MDSenior Medical Director

Kalpna Gupta, University of Minnesota

PhDDivision of Hematology, Oncology and TransplantationDepartment of Medicine