Review Articles
Vol. 1 No. 1 (2009): Progress in Diagnosis and Therapy of Thalassemia and Hemoglobinopathies

COAGULOPATHY IN BETA-THALASSEMIA: CURRENT UNDERSTANDING AND FUTURE PERSPECTIVES

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Published: December 28, 2009
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, thalassemia, hypercoagulability, thromboembolism, stroke.
Hematology

Authors

M. Domenica Cappellini
maria.cappellini@unimi.it
1Universitá di Milano, Policlinico Foundation IRCCS, Milan, Italy, Italy.
Khaled M. Musallam
2Department of Internal Medicine, Hematology-Oncology Division, American University of, .
Alessia Marcon
Ali Taher

As the life expectancy of β-thalassemia patients has markedly improved over the last decade, several new complications are being recognized. The presence of a high incidence of thromboembolic events, mainly in thalassemia intermedia patients, has led to the identification of a hypercoagulable state in thalassemia. In this review, the molecular and cellular mechanisms leading to hypercoagulability in thalassemia are highlighted, and the current clinical experience is summarized. Recommendations for thrombosis prophylaxis are also discussed.

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Citations

M. Domenica Cappellini, 1Universitá di Milano, Policlinico Foundation IRCCS, Milan, Italy
Institute of Hematology, Catholic University, Director

How to Cite



“COAGULOPATHY IN BETA-THALASSEMIA: CURRENT UNDERSTANDING AND FUTURE PERSPECTIVES” (2009) Mediterranean Journal of Hematology and Infectious Diseases, 1(1), p. e2009029. Available at: https://www.mjhid.org/mjhid/article/view/2009.029 (Accessed: 11 March 2026).