Case Reports
Vol. 3 No. 1 (2011): Reviews, Articles, Case Reports and Letters
https://doi.org/10.4084/mjhid.2011.010

Severe Acute Hepatitis B Treated with Entecavir

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Published: March 14, 2011
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Acute Hepatitis B, Entecavir, HBV therapy
Infectious Diseases

Authors

Giuseppe Vittorio Luigi De Socio
giuseppedesocio@yahoo.it
Clinica di Malattie Infettive, Azienda ospedaliera di Perugia, Italy.
Alessio Sgrelli
Clinica di Malattie Infettive, Università di Perugia, Italy.
Andrea Tosti
Clinica di Malattie Infettive, Azienda ospedaliera di Perugia, Italy.
Franco Baldelli
Clinica di Malattie Infettive, Università di Perugia, Italy.
Hepatitis B virus (HBV) infection constitutes a serious global health problem. Nowadays there are divergent data regarding the use of antiviral drugs to treat acute hepatitis B. We present here a case of a 62-year-old man affected by severe acute hepatitis B with progressive worsening of clinical and hepatic function. The patient was treated with entecavir without critical side effects. We observed rapid clinical and laboratory improvements and the disappearance of surface antigen (HBsAg). The treatment with entecavir was protracted until 17th week when the antibody antiHBs (anti HBs) appeared. Entecavir should be carefully considered for the treatment of severe acute hepatitis B cases.

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“Severe Acute Hepatitis B Treated with Entecavir” (2011) Mediterranean Journal of Hematology and Infectious Diseases, 3(1), p. e2011010. doi:10.4084/mjhid.2011.010.