Case Reports
Vol. 4 No. 1 (2012): Reviews, Articles, Case Reports and Letters
Transfusion associated peak in Hb HPLC chromatogram – a case report
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Published: January 21, 2012
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Hematology
Authors
High performance liquid chromatography (HPLC) and electrophoresis are commonly used to diagnose various hemoglobinopathies. However, insufficient information about the transfusion history can lead to unexpected and confusing results. We are reporting a case of Juvenile myelomonocytic leukemia (JMML) in which HbHPLC was done to quantify fetal hemoglobin (HbF). The chromatogram showed elevated HbF along with a peak in the HbD window. A transfusion acquired peak was suspected based on the unexpectedly low percentage of HbD and was subsequently confirmed using parental HbHPLC.
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EditorialsHow to Cite
“Transfusion associated peak in Hb HPLC chromatogram – a case report” (2012) Mediterranean Journal of Hematology and Infectious Diseases, 4(1), p. e2012006. doi:10.4084/mjhid.2012.006.
