Review Articles
Vol. 6 No. 1 (2014): Reviews, Articles, Case Reports and Letters
IMMUNOLOGICAL DEREGULATION IN HODGKIN’S DISEASE
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Published: May 29, 2014
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Hodgkin’s Disease (HD) has a unique histology since only a few neoplastic cells are surrounded by inflammatory accessory cells that in the last years have emerged as crucial players in sustaining the course of disease. In addition, recent studies suggest that the abnormal activity of these inflammatory cells (such as deregulation in Tregsignaling, expansion of myeloid derived suppressor cells, HLA-G signaling and NK dysfunction) may have prognostic significance. This review is focused on summarizing recent advanced in immunological defects in HD with translational implications.
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How to Cite
“IMMUNOLOGICAL DEREGULATION IN HODGKIN’S DISEASE” (2014) Mediterranean Journal of Hematology and Infectious Diseases, 6(1), p. e2014039. doi:10.4084/mjhid.2014.039.
