Case Reports
Vol. 8 (2016): Review, Original Articles, Case Reports
https://doi.org/10.4084/mjhid.2016.027

Massive pulmonary embolism at the onset of acute promyelocytic leukemia

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Received: March 2, 2016
Accepted: May 15, 2016
Published: July 1, 2016
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acute promyelocytic leukemia, pulmonary embolism, thrombolysis, arsenic trioxide.
haematology

Authors

Federica Sorà
f.sora@rm.unicatt.it
Patrizia Chiusolo
, Luca Laurenti, Francesco Autore, Sabrina Giammarco and Simona Sica, .
Luca Laurenti
Life-threatening bleeding is a major and early complication of acute promyelocytic leukemia (APL), but in the last years there is a growing evidence of thromboses in  APL. We report the first case of a young woman with dyspnea as the first symptom of APL due to massive pulmonary embolism (PE) successfully treated with thrombolysis for PE and heparin. APL has been processed with a combination of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) obtaining complete remission.

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case report

How to Cite



“Massive pulmonary embolism at the onset of acute promyelocytic leukemia” (2016) Mediterranean Journal of Hematology and Infectious Diseases, 8, p. e2016027. doi:10.4084/mjhid.2016.027.