Scientific Letters
Vol. 8 (2016): Review, Original Articles, Case Reports
https://doi.org/10.4084/mjhid.2016.055

Fetal hemoglobin modifies the disease manifestation of severe Plasmodium falciparum malaria in adult patients with sickle cell anemia.

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Received: July 10, 2016
Accepted: October 14, 2016
Published: November 1, 2016
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Plasmodium falciparum, Malaria, Sickle Cell Anemia, HbF
Hematology, Infectious Diseases

Authors

Prasanta Purohit
prasanta.biochem@gmail.com
Senior Research Fellow Indian Council of Medical Research (ICMR) Sickle Cell Clinic and Molecular Biology Laboratory, Veer Surendra Sai Institute of Medical Sciences and Research (VIMSAR), Burla, Odisha, India.
Sickle cell anemia (SCA) and Plasmodium falciparum malaria are two major public health problems in the state of Odisha, India. The prevalence of sickle cell gene in the western part of Odisha is 13.1%,1P. falciparum contributes 23% of cases and 15% of malaria-related deaths in India. Various......

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World Health Organization: Guidelines for the Treatment of Malaria, 2nd ed. Geneva, World Health Organization, 2010 (who.int/malaria/publications/atoz/9789241547925/en/.)
Mashon RS, Dash PM, Khalko J, et al., Higher fetal hemoglobin concentration in patients with sickle cell disease in eastern India reduces frequency of painful crisis. European Journal of Hematology. 2009; 83(4):383-384.

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“Fetal hemoglobin modifies the disease manifestation of severe Plasmodium falciparum malaria in adult patients with sickle cell anemia”. (2016) Mediterranean Journal of Hematology and Infectious Diseases, 8, p. e2016055. doi:10.4084/mjhid.2016.055.