Scientific Letters
Vol. 13 No. 1 (2021): Mediterranean Journal of Hematology and Infectious Diseases, Volume 13, 2021
Cytomorphology of Chimeric Antigen Receptor T-Cells (CAR-T)
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All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Received: September 7, 2021
Accepted: October 9, 2021
Accepted: October 9, 2021
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Chimeric antigen receptor (CAR) T cells represent one of the newest frontiers of cell therapy. Their application currently involves relapsed/refractory aggressive B cell lymphoma and leukemia as a standard of care, while several studies are exploring CAR-T to treat multiple myeloma and other hematological malignancies. Here we describe the cytomorphology of CAR-T collected from the leftovers of infusion bags, and therefore before the encounter with the antigen, with, among others, a peculiar population of giant lymphoid cells with blastoid features and hypertrophic centrosome.
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Citations
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Cytomorphology of CAR-T cellsHow to Cite
“Cytomorphology of Chimeric Antigen Receptor T-Cells (CAR-T)” (2021) Mediterranean Journal of Hematology and Infectious Diseases, 13(1), p. e2021066. doi:10.4084/MJHID.2021.066.
Copyright (c) 2021 Eugenio Galli, Silvia Bellesi, Marcello Viscovo, Federica Sorà, Stefan Hohaus, Nicola Piccirillo, Luca Laurenti, Patrizia Chiusolo, Valerio De Stefano, Simona Sica, Gina Zini
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
